SCHEMBL5581970

SCHEMBL5581970

CC(Cl)[SiH](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1164694 0.74
SCHEMBL2556849 0.71
SCHEMBL7725 0.71
SCHEMBL467632 0.70
SCHEMBL41781 0.67
SCHEMBL7256997 0.67
SCHEMBL28798423 0.67
SCHEMBL10499328 0.67
SCHEMBL5438089 0.65
SCHEMBL17222435 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2732063-B1 METHOD OF PROVIDING A MULTIFUNCTIONAL COATING ON A METAL SUBSTRATE TATA STEEL UK LTD (GB) 2015-12-16 EP claimed
US-20070181873-A1 Organic-inorganic hybrid polymer and organic insulator composition having the same and methods thereof SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-08-09 US claimed
EP-3428200-B1 POLYMERIZATION CATALYST, COPOLYMER, POLYMER COMPOSITION, AND CROSSLINKED POLYMER JSR CORP (JP) 2022-05-04 EP disclosed
US-10906996-B2 Polymerization catalyst, copolymer, polymer composition, and crosslinked polymer JSR CORPORATION (JP) 2021-02-02 US disclosed
US-20190048107-A1 POLYMERIZATION CATALYST, COPOLYMER, POLYMER COMPOSITION, AND CROSSLINKED POLYMER JSR CORPORATION (JP) 2019-02-14 US disclosed
EP-3428200-A1 POLYMERIZATION CATALYST, COPOLYMER, POLYMER COMPOSITION, AND CROSSLINKED POLYMER JSR Corporation (JP) 2019-01-16 EP disclosed
CN-105289742-B For the catalyst of ethylene selectivity oligomerisation, ligand and preparation method thereof 天津科技大学 2018-07-13 CN disclosed
US-20070181873-A1 Organic-inorganic hybrid polymer and organic insulator composition having the same and methods thereof SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-08-09 US disclosed
CN-1207298-C Triazolopurine derivatives, drug compositions containing the same and adenosine A3 receptor affinitive agents OTSUKA PHARMA CO LTD (JP) 2005-06-22 CN disclosed
US-20040142952-A1 Triazoloquinazoline and pyrazolotriazolopyrimidine derivatives, medicinal compositions, adenosine a3 receptor affinity agents, ocular tension lowering agents, preparations for preventing and treating glaucoma and method of lowering ocular tension OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2004-07-22 US disclosed
EP-1227098-B1 TRIAZOLOPURINE DERIVATIVES, DRUG COMPOSITIONS CONTAINING THE SAME AND ADENOSINE A3 RECEPTOR AFFINITIVE AGENTS OTSUKA PHARMA CO LTD (JP) 2004-04-28 EP disclosed
CN-1491227-A Triazoloquinazoline and pyrazolotriazolopyrimidine derivatives, medicinal compositions, adenosine A3 receptor affinity agents, ocular tension lowering agents, preparations for preventing and treating 株式会社大V制药工厂 2004-04-21 CN disclosed
US-6686343-B1 Triazolopurine derivatives, pharmaceutical compositions containing the derivatives, and adenosine A3 receptor affinitive agents OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2004-02-03 US disclosed
EP-1364953-A1 TRIAZOLOQUINAZOLINE AND PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES, MEDICINAL COMPOSITIONS, ADENOSINE A3 RECEPTOR AFFINITY AGENTS, OCULAR TENSION LOWERING AGENTS, PREPARATIONS FOR PREVENTING AND TREATING GLAUCOMA AND METHOD OF LOWERING OCULAR TENSION OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2003-11-26 EP disclosed
CN-1376157-A Triazolopurine derivatives, drug compositions containing the same and adenosine A3 receptor affinitive agents OTSUKA PHARMA CO LTD (JP) 2002-10-23 CN disclosed
EP-1227098-A1 TRIAZOLOPURINE DERIVATIVES, DRUG COMPOSITIONS CONTAINING THE SAME AND ADENOSINE A3 RECEPTOR AFFINITIVE AGENTS OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2002-07-31 EP disclosed
EP-0749974-B1 PHOSPHONIC DIESTER DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2001-06-27 EP disclosed
US-5922866-A REACTING A TRIALKYLSILYL HALIDE WITH A 1,2-AMIDE SUBSTITUTED BENZENE DERIVATIVE IN THE PRESENCE OF A BASE; USE AS PHARMACEUTICALS OR INTERMEDIATES FOR SYNTHESIS THEREOF, SUCH AS ANTIDIABETIC DRUGS OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1999-07-13 US disclosed
US-5798344-A TREATING DIABETES, HYPERLIPIDEMIA OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1998-08-25 US disclosed
EP-0749974-A1 PHOSPHONIC DIESTER DERIVATIVE OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 1996-12-27 EP disclosed