SCHEMBL5582099

SCHEMBL5582099

N#CC(O)c1ccco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9669855 1.00
SCHEMBL27536763 1.00
SCHEMBL10480476 0.78 KMT2A (0.44)
SCHEMBL11702005 0.77
SCHEMBL6971969 0.77
SCHEMBL8392647 0.76 KMT2A (0.40)
SCHEMBL15272598 0.75 KMT2A (0.58)
SCHEMBL11151822 0.75 KMT2A (0.58)
SCHEMBL15272327 0.75 KMT2A (0.58)
SCHEMBL10768232 0.74 KMT2A (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119118967-A Preparation method of 2-furanone acid 重庆新征程生物医药有限公司 2024-12-13 CN claimed
EP-0510689-A1 Hydrocyanation of pentenenitriles using cyanohydrins E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-28 EP claimed
US-5107012-A Using an additive to promote dissociation of the cyanohydrin, a nickel complex catalyst and catalyst promoter; slurrying E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-21 US claimed
CN-119118967-A Preparation method of 2-furanone acid 重庆新征程生物医药有限公司 2024-12-13 CN disclosed
CN-119118967-A Preparation method of 2-furanone acid 重庆新征程生物医药有限公司 2024-12-13 CN disclosed
EP-2210889-A1 Process for producing pyrimidine compound Eisai R&D Management Co., Ltd. (JP) 2010-07-28 EP disclosed
EP-1862463-A1 PYRIMIDINE COMPOUND CRYSTAL OR AMORPHOUS FORM AND PROCESS FOR PRODUCING THE SAME Eisai R&D Management Co., Ltd. (JP) 2007-12-05 EP disclosed
US-7300784-B2 Nitrile hydratase and a method for producing amides DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2007-11-27 US disclosed
EP-1160235-B1 A method for producing alpha-hydroxycarboxylic acid NIPPON CATALYTIC CHEM IND (JP) 2006-09-20 EP disclosed
US-6900037-B2 Method for producing amide compounds DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2005-05-31 US disclosed
US-6864389-B2 Method for producing α-hydroxycarboxylic acid NIPPON SHOKUBAI CO., LTD. (JP) 2005-03-08 US disclosed
EP-0365045-A1 Perhydrothiazepine derivatives, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1990-04-25 EP disclosed
US-4859784-A Process for the production of optically active cyanohydrins DEGUSSA AKTIENGESELLSCHAFT (DE) 1989-08-22 US disclosed
EP-0276375-A2 Process for the preparation of optically active alpha-hydroxynitriles Degussa Aktiengesellschaft (DE) 1988-08-03 EP disclosed
US-4699905-A HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 1987-10-13 US disclosed
EP-0161801-A2 Perhydrothiazepine derivatives, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1985-11-21 EP disclosed
US-4107178-A Thioprene or furan derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JP) 1978-08-15 US disclosed
US-4086420-A Thioprene or furan derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JA) 1978-04-25 US disclosed
US-4076732-A Derivatives of α-(6-carboxyhexyl) furfuryl alcohol AMERICAN CYANAMID COMPANY (US) 1978-02-28 US disclosed
US-4051151-A Thiophene derivatives and process for preparation thereof SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-09-27 US disclosed