⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6894366 | 0.77 | — | — | |
| SCHEMBL974911 | 0.69 | TSHR (0.36) | — | |
| SCHEMBL22761741 | 0.69 | — | — | |
| SCHEMBL4793302 | 0.69 | — | — | |
| SCHEMBL6223484 | 0.67 | — | — | |
| SCHEMBL3304951 | 0.66 | EPHX1 (0.41) | — | |
| SCHEMBL1158383 | 0.65 | — | — | |
| SCHEMBL10832324 | 0.65 | — | — | |
| SCHEMBL2840847 | 0.65 | — | — | |
| SCHEMBL44498 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030204080-A1 | Methods for producing nucleoside derivatives and intermediates therefor | AJINOMOTO CO. INC (JP) | 2003-10-30 | — | — | US | claimed |
| US-20030004330-A1 | Methods for producing nucleoside derivatives and intermediates therefor | AJINOMOTO CO. INC (JP) | 2003-01-02 | — | — | US | claimed |
| EP-1052265-A1 | PROCESS FOR PRODUCING NUCLEOSIDE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-11-15 | — | — | EP | claimed |
| EP-0945460-A1 | Methods for producing nucleoside derivatives and intermediates therefore | Ajinomoto Co., Inc. (JP) | 1999-09-29 | — | — | EP | claimed |
| JP-5025180-A | — | — | None | — | — | JP | disclosed |
| JP-5310621-A | — | — | None | — | — | JP | disclosed |
| EP-1809301-B1 | 2-FLUORO-2-ALKYL-SUBSTITUTED D-RIBONOLACTONE INTERMEDIATES | GILEAD PHARMASSET LLC (US) | 2019-11-06 | — | — | EP | disclosed |
| EP-3109244-A2 | PREPARATION OF 2'FLUORO-2'-ALKYL-SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES | Gilead Pharmasset LLC (US) | 2016-12-28 | — | — | EP | disclosed |
| CN-101437524-B | Preparation of 2 '-fluoro-2' -alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives | PHARMASSET LTD | 2012-01-11 | — | — | CN | disclosed |
| CN-101437524-A | Preparation of 2 '-fluoro-2' -alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and derivatives thereof | PHARMASSET INC (US) | 2009-05-20 | — | — | CN | disclosed |
| EP-1809301-A2 | PREPARATION OF 2'FLUORO-2'-ALKYL-SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES | Pharmasset, Inc. (US) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006031725-A2 | PREPARATION OF 2'FLUORO-2'- ALKYL- SUBSTITUTED OR OTHER OPTIONALLY SUBSTITUTED RIBOFURANOSYL PYRIMIDINES AND PURINES AND THEIR DERIVATIVES | PHARMASSET, INC. (US) | 2006-03-23 | — | — | WO | disclosed |
| EP-1052265-A1 | PROCESS FOR PRODUCING NUCLEOSIDE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-11-15 | — | — | EP | disclosed |
| US-6090937-A | Methods for producing nucleoside derivatives and intermediates therefor | AJINOMOTO CO., INC. (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0945460-A1 | Methods for producing nucleoside derivatives and intermediates therefore | Ajinomoto Co., Inc. (JP) | 1999-09-29 | — | — | EP | disclosed |
| JP-H05310621-A | APHIDICHOLANE DERIVATIVE AND ITS PRODUCTION | NIPPON MEKTRON LTD | 1993-11-22 | — | — | JP | disclosed |
| JP-H0525180-A | OPTICALLY ACTIVE PYRANOBENZOXADIAZOLE COMPOUND AND ITS PRODUCTION | NISSAN CHEM IND LTD | 1993-02-02 | — | — | JP | disclosed |
| EP-0285526-A2 | 1-N-(4-Amino-3-fluoro-2-hydroxybutyryl)-kanamycins | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1988-10-05 | — | — | EP | disclosed |
| US-4308277-A | IMMUNOREGULATORY, ANTITHROMBOTIC, ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1981-12-29 | — | — | US | disclosed |
| JP-H00525180-A | — | — | 0001-01-01 | — | — | JP | disclosed |