SCHEMBL5582525

SCHEMBL5582525

CC(=O)OC(c1ccc(NC(=O)c2ccc(-c3ccc(Cl)cc3)cc2)cc1)C1CCCNC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14454827 0.84
Hydrochloric Acid SCHEMBL5582548 0.83 SLC2A1 (0.50)
SCHEMBL14454824 0.76
Hydrochloric Acid SCHEMBL5582999 0.75 SLC2A1 (0.53)
SCHEMBL2069658 0.75 SLC6A4 (0.67)
SCHEMBL21681674 0.74
SCHEMBL14454834 0.74
SCHEMBL1994479 0.73
SCHEMBL1990352 0.73
SCHEMBL1991618 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 US claimed
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 US disclosed
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 US disclosed
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 US disclosed
US-7115750-B1 Melanin concentrating hormone antagonist TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-10-03 US disclosed