SCHEMBL5583097

SCHEMBL5583097

CN(C)CC1Cc2ccc(NC(=O)c3ccc(-c4ccc(Cl)cc4)cc3)cc2C1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 18/20 0.84
SLC2A1 P11166 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14454779 0.92 MCHR1 (1.00) MCHR1SLC2A1
SCHEMBL5582975 0.90 MCHR1 (0.89) MCHR1SLC2A1
SCHEMBL5583036 0.86 MCHR1 (0.69) MCHR1
SCHEMBL14454797 0.83 MCHR1 (1.00) MCHR1SLC2A1
SCHEMBL5582998 0.83 MCHR1 (0.84) MCHR1SLC2A1
SCHEMBL14454795 0.82 MCHR1 (0.82) MCHR1SLC2A1
SCHEMBL14454794 0.82 MCHR1 (1.00) MCHR1
SCHEMBL5582618 0.82 MCHR1 (0.85) MCHR1
SCHEMBL14454784 0.82 MCHR1 (0.85) MCHR1
SCHEMBL14454781 0.82 MCHR1 (1.00) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 US disclosed
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 US disclosed
US-20070173498-A1 Melanin concentrating hormone antagonist KATO KANEYOSHI 2007-07-26 US disclosed
US-7115750-B1 Melanin concentrating hormone antagonist TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173498-A1 Melanin concentrating hormone antagonist MC1R, MCHR1, MCHR2 MCHR1 2/4885SLC2A1 1211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.