Mannose 6-Phosphate

Mannose 6-Phosphate

SCHEMBL5583695

CC(=O)OP(=O)(O)O.O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)COP(=O)(O)O

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MPI P34949 1/20 0.58
PGD P52209 5/20 0.42
PGK1 P00558 1/20 0.38
PGK2 P07205 1/20 0.38
S1PR4 O95977 2/20 0.32
S1PR1 P21453 2/20 0.32
S1PR3 Q99500 2/20 0.32
S1PR5 Q9H228 2/20 0.32
S1PR2 O95136 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSPO P30536 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mannose 6-Phosphate SCHEMBL2319337 0.87 MPI (0.75) MPIPGDPGK1PGK2S1PR4
Mannose 6-Phosphate SCHEMBL1874195 0.87 MPI (0.75) MPIPGDPGK1PGK2S1PR4
Mannose 6-Phosphate SCHEMBL9736768 0.87 MPI (0.75) MPIPGDPGK1PGK2S1PR4
Mannose 6-Phosphate SCHEMBL9739836 0.87 MPI (0.75) MPIPGDPGK1PGK2S1PR4
Mannose 6-Phosphate SCHEMBL6599 0.87 MPI (0.75) MPIPGDPGK1PGK2S1PR4
Mannose 6-Phosphate SCHEMBL9738212 0.87 MPI (0.75) MPIPGDPGK1PGK2S1PR4
Mannose 6-Phosphate SCHEMBL8488 0.87 MPI (0.75) MPIPGDPGK1PGK2S1PR4
Mannose 6-Phosphate SCHEMBL5790782 0.87 MPI (0.75) MPIPGDPGK1PGK2S1PR4
Mannose 6-Phosphate SCHEMBL20798006 0.87 MPI (0.75) MPIPGDPGK1PGK2S1PR4
Mannose 6-Phosphate SCHEMBL5789525 0.87 MPI (0.75) MPIPGDPGK1PGK2S1PR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120190064-A1 FEEDING BUFFERS, SYSTEMS, AND METHODS FOR IN VITRO SYNTHESIS OF BIOMOLECULES Life Technologies Corporation (US) 2012-07-26 US disclosed
EP-1848812-A2 FEEDING BUFFERS, SYSTEMS, AND METHODS FOR IN VITRO SYNTHESIS OF BIOMOLECULES INVITROGEN CORPORATION (US) 2007-10-31 EP disclosed
US-20060110788-A1 Feeding buffers, systems, and methods for in vitro synthesis of biomolecules INVITROGEN CORPORATION (US) 2006-05-25 US disclosed
WO-2006039622-A2 FEEDING BUFFERS, SYSTEMS, AND METHODS FOR IN VITRO SYNTHESIS OF BIOMOLECULES INVITROGEN CORPORATION (US) 2006-04-13 WO disclosed