SCHEMBL5583911

SCHEMBL5583911

C(/C=C/c1ccccc1)=C\c1ccccc1.[SiH4].[Ti]

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.88
MAPK1 P28482 2/20 0.62
TRPA1 O75762 2/20 0.62
ALDH1A1 P00352 2/20 0.62
LMNA P02545 2/20 0.62
ALOX5 P09917 1/20 0.62
HDAC3 O15379 2/20 0.52
HDAC4 P56524 2/20 0.52
HDAC1 Q13547 2/20 0.52
HDAC7 Q8WUI4 2/20 0.52
HDAC2 Q92769 2/20 0.52
HDAC10 Q969S8 2/20 0.52
HDAC11 Q96DB2 2/20 0.52
HDAC8 Q9BY41 2/20 0.52
HDAC6 Q9UBN7 2/20 0.52
HDAC9 Q9UKV0 2/20 0.52
HDAC5 Q9UQL6 2/20 0.52
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
MAPT P10636 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583913 1.00 MAOB (0.88) MAOBMAPK1TRPA1ALDH1A1LMNA
SCHEMBL2232008 0.97 MAOB (0.93) MAOBMAPK1TRPA1ALDH1A1LMNA
SCHEMBL2232004 0.97 MAOB (0.93) MAOBMAPK1TRPA1ALDH1A1LMNA
SCHEMBL23458007 0.94 MAOB (1.00) MAOBMAPK1TRPA1ALDH1A1LMNA
SCHEMBL5875512 0.94 MAOB (1.00) MAOBMAPK1TRPA1ALDH1A1LMNA
Benzene SCHEMBL135524 0.94 MAOB (1.00) MAOBMAPK1TRPA1ALDH1A1LMNA
SCHEMBL6853572 0.94 MAOB (1.00) MAOBMAPK1TRPA1ALDH1A1LMNA
SCHEMBL592744 0.94 MAOB (1.00) MAOBMAPK1TRPA1ALDH1A1LMNA
Benzene SCHEMBL9803304 0.94 MAOB (1.00) MAOBMAPK1TRPA1ALDH1A1LMNA
SCHEMBL39483 0.94 MAOB (1.00) MAOBMAPK1TRPA1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109952324-B Blocked multi-or double-headed compositions suitable for chain shuttling and methods of making the same 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
CN-110546171-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2023-02-28 CN disclosed
CN-115260366-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-11-01 CN disclosed
CN-109937217-A The bull or double end composition that are moved suitable for chain shuttle and preparation method 陶氏环球技术有限责任公司 2019-06-25 CN disclosed
EP-1377613-B1 METHOD OF MAKING INTERPOLYMERS AND PRODUCTS MADE THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2019-06-19 EP disclosed
EP-1412398-B1 HIGH MELT STRENGTH POLYMERS AND METHOD OF MAKING SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2019-04-24 EP disclosed
CN-108026115-A The bull shuttled available for chain or double end composition and preparation method thereof 陶氏环球技术有限责任公司 2018-05-11 CN disclosed
CN-104892814-B The method of selective polymerization modifying agent 陶氏环球技术有限责任公司 2017-11-10 CN disclosed
CN-101142247-A Pseudo-block copolymers and methods of using chain shuttling agents DOW GLOBAL TECHNOLOGIES INC (US) 2008-03-12 CN disclosed
US-7271221-B2 Method of making interpolymers and products made therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2007-09-18 US disclosed
CN-1255439-C High melt strength polymers and methods of making the same DOW GLOBAL TECHNOLOGIES CO (US) 2006-05-10 CN disclosed
US-6924342-B2 Method of making interpolymers and products made therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2005-08-02 US disclosed
US-20050065286-A1 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES LLC 2005-03-24 US disclosed
US-20050020778-A1 High melt strength polymers and method of making same DOW GLOBAL TECHNOLOGIES LLC 2005-01-27 US disclosed
EP-1412398-A2 HIGH MELT STRENGTH POLYMERS AND METHOD OF MAKING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2004-04-28 EP disclosed
US-20030088037-A1 Method of making interpolymers and products made therefrom THE DOW CHEMICAL COMPANY (US) 2003-05-08 US disclosed
US-20030050411-A1 Use of polar monomers in olefin polymerization and polymers thereof DOW GLOBAL TECHNOLOGIES INC. 2003-03-13 US disclosed
WO-2002100906-A1 USE OF POLAR MONOMERS IN OLEFIN POLYMERIZATION AND POLYMERS THEREOF DOW GLOBAL TECHNOLOGIES INC. (US) 2002-12-19 WO disclosed
WO-2002074816-A2 HIGH MELT STRENGTH POLYMERS AND METHOD OF MAKING SAME DOW GLOBAL TECHNOLOGIES INC. (US) 2002-09-26 WO disclosed