Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.48 |
| ▸ | BCL3 | P20749 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13390549 | 0.74 | HDAC1 (0.62) | HDAC1BCL3ALDH1A1GAAHDAC2 | |
| SCHEMBL13646217 | 0.72 | HDAC1 (0.61) | HDAC1ALDH1A1HDAC2HDAC3HDAC4 | |
| SCHEMBL5584036 | 0.70 | HDAC1 (0.62) | HDAC1GAA | |
| SCHEMBL3558274 | 0.70 | HDAC1 (0.71) | HDAC1ALDH1A1HDAC2HDAC3HDAC4 | |
| SCHEMBL211110 | 0.69 | HDAC1 (0.80) | HDAC1 | |
| SCHEMBL3546995 | 0.68 | HDAC1 (0.56) | HDAC1BCL3ALDH1A1GAAHDAC2 | |
| SCHEMBL17554020 | 0.67 | BCL3 (0.76) | BCL3ALDH1A1GAAPOLB | |
| SCHEMBL210528 | 0.67 | HDAC1 (0.70) | HDAC1HDAC2HDAC3HDAC11HDAC8 | |
| SCHEMBL2407119 | 0.66 | HDAC1 (0.56) | HDAC1BCL3ALDH1A1GAAHDAC2 | |
| SCHEMBL2407116 | 0.66 | HDAC1 (0.56) | HDAC1BCL3ALDH1A1GAAHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7253204-B2 | Antiproliferative agents | METHYLGENE INC. (CA) | 2007-08-07 | — | — | US | disclosed |
| US-20050245518-A1 | Antiproliferative agents | METHYLGENE, INC. | 2005-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245518-A1 | Antiproliferative agents | HDAC1, HDAC11, HDAC5 | HDAC1 1/4885BCL3 257/4885ALDH1A1 758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.