SCHEMBL5586152

SCHEMBL5586152

C=C(C)C(N)=O.C=C(CCO)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.57
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35589 0.90
Ammonia Solution, Strong SCHEMBL27894735 0.87
SCHEMBL30888177 0.87
SCHEMBL9773632 0.83 TDP1 (0.33) TDP1LMNA
Ethylene Glycol SCHEMBL860665 0.82 TDP1 (0.75) TDP1LMNAALOX15BLMPMP22
Ethylene Glycol SCHEMBL1275662 0.82 TDP1 (0.75) TDP1LMNAALOX15BLMPMP22
Phosphoric Acid SCHEMBL16371968 0.81 TDP1 (0.32) TDP1
Acetone SCHEMBL1788346 0.81 TDP1 (0.57) TDP1LMNAALOX15BLMPMP22
Phosphoric Acid SCHEMBL16372120 0.81 TDP1 (0.32) TDP1
SCHEMBL28170977 0.81 TDP1 (0.57) TDP1LMNAALOX15BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7176297-B2 Photoactivatable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2007-02-13 US claimed
US-20040234788-A1 Photoactivateable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. 2004-11-25 US claimed
US-6773888-B2 ARRAY OF OLIGONUCLEOTIDES; FUNCTIONALIZED POLYMER, A PHOTOACTIVATABLE SILANE COMPOUND CAPABLE OF PHOTOCHEMICALLY CROSS-LINKING TO SAID FUNCTIONALIZED POLYMER. AFFYMETRIX, INC. 2004-08-10 US claimed
WO-2003087166-A2 PHOTOACTIVATABLE SILANE COMPOUNDS AND METHODS FOR THEIR SYNTHESIS AND USE AFFYMETRIX, INC. (US) 2003-10-23 WO claimed
US-20030194715-A1 Photoactivatable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2003-10-16 US claimed
US-7176297-B2 Photoactivatable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2007-02-13 US disclosed
US-20040234788-A1 Photoactivateable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. 2004-11-25 US disclosed
US-6773888-B2 ARRAY OF OLIGONUCLEOTIDES; FUNCTIONALIZED POLYMER, A PHOTOACTIVATABLE SILANE COMPOUND CAPABLE OF PHOTOCHEMICALLY CROSS-LINKING TO SAID FUNCTIONALIZED POLYMER. AFFYMETRIX, INC. 2004-08-10 US disclosed
WO-2003087166-A2 PHOTOACTIVATABLE SILANE COMPOUNDS AND METHODS FOR THEIR SYNTHESIS AND USE AFFYMETRIX, INC. (US) 2003-10-23 WO disclosed
US-20030194715-A1 Photoactivatable silane compounds and methods for their synthesis and use AFFYMETRIX, INC. (US) 2003-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030194715-A1 Photoactivatable silane compounds and methods for their synthesis and use PCNA, GMNN, LSS TDP1 4201/4885LMNA 13/4885ALOX15 920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.