Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.87 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.58 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1875686 | 0.93 | MAPK14 (1.00) | MAPK14MAPK9MAPK10MAPK11SCD | |
| SCHEMBL1881929 | 0.90 | MAPK14 (1.00) | MAPK14MAPK9MAPK10MAPK11MAPT | |
| SCHEMBL1880630 | 0.87 | MAPK14 (0.77) | MAPK14MAPK9MAPK10MAPK11MAPT | |
| SCHEMBL1879555 | 0.85 | MAPK14 (0.79) | MAPK14MAPK9MAPK10MAPK11CYP3A4 | |
| SCHEMBL1881124 | 0.85 | MAPK14 (0.82) | MAPK14MAPK9MAPK10MAPK11MAPT | |
| SCHEMBL1877888 | 0.85 | MAPK14 (0.82) | MAPK14MAPK9MAPK10MAPK11SCD | |
| SCHEMBL1884227 | 0.85 | MAPK14 (0.75) | MAPK14MAPK9MAPK10MAPK11CYP3A4 | |
| SCHEMBL1880734 | 0.84 | MAPK14 (0.80) | MAPK14MAPK9MAPK10MAPK11SCD | |
| SCHEMBL1880828 | 0.84 | MAPK14 (0.86) | MAPK14MAPK9MAPK10MAPK11PRKACA | |
| SCHEMBL1875693 | 0.83 | MAPK14 (0.82) | MAPK14MAPK9MAPK10MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1832584-A1 | PYRIMIDINYLISOXAZOL DERIVATIVE | ASKA Pharmaceutical Co., Ltd. (JP) | 2007-09-12 | — | — | EP | disclosed |