Ethylene

Ethylene

SCHEMBL5586541

C=C.C=CC(=O)OC(N)C=C

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.35
ALDH1A1 P00352 5/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
FGFR4 P22455 1/20 0.33
HSD17B10 Q99714 1/20 0.33
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
BLM P54132 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MEN1 O00255 1/20 0.31
CYP2D6 P10635 1/20 0.31
NFKB1 P19838 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35770 0.98
Hydrochloric Acid SCHEMBL6416074 0.95 TSHR (0.35) TSHRALDH1A1TP53HIF1ACYP3A4
Acrylamide SCHEMBL5945502 0.91 TSHR (0.48) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL156789 0.77 TSHR (0.34) TSHRALDH1A1FGFR4SLC6A2SLC6A4
SCHEMBL6017112 0.77
SCHEMBL11245978 0.76 HCAR2 (0.52) TSHRALDH1A1TP53SLC6A2SLC6A4
SCHEMBL237880 0.75
SCHEMBL1489814 0.75
SCHEMBL3778981 0.73
SCHEMBL117941 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7175918-B2 Polyolefin compositions EQUISTAR CHEMICALS, LP (US) 2007-02-13 US disclosed
US-20050239961-A1 Polyolefin compositions LYONDELL CHEMICAL TECHNOLOGY, LP 2005-10-27 US disclosed
US-6562081-B2 Dye blends from the primary color group at a concentration of 75-100% of the determined maximum concentration which produces crocking EQUISTAR CHEMICALS, LP 2003-05-13 US disclosed
US-20030019054-A1 Disperse dyed polyethylene and process EQUISTAR CHEMICALS, LP 2003-01-30 US disclosed
EP-0770156-A4 DYEABLE POLYOLEFIN COMPOSITIONS AND METHOD LYONDELL PETROCHEM (US) 1998-03-11 EP disclosed
EP-0770156-A1 DYEABLE POLYOLEFIN COMPOSITIONS AND METHOD LYONDELL PETROCHEMICAL COMPANY (US) 1997-05-02 EP disclosed
US-5576366-A CATIONIC DYES LYONDELL PETROCHEMICAL COMPANY (US) 1996-11-19 US disclosed
US-5550192-A USING A DISPERSE DYE LYONDELL PETROCHEMICAL COMPANY (US) 1996-08-27 US disclosed
WO-1995033882-A1 DYEABLE POLYOLEFIN COMPOSITIONS AND METHOD LYONDELL PETROCHEMICAL COMPANY (US) 1995-12-14 WO disclosed
US-5468259-A Polypropylene fibers exposed to disperse dyes EQUISTAR CHEMICALS, LP 1995-11-21 US disclosed
US-3711435-A STABLE AQUEOUS DISPERSIONS OF ETHYLENE AMINOALKYL ACRYLATE COPOLYMERS DU PONT 1973-01-16 US disclosed