Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.79 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.73 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.63 |
| ▸ | SHBG | P04278 | 2/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.63 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | AR | P10275 | 2/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | SNCA | P37840 | 2/20 | 0.63 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.63 |
| ▸ | CYP51A1 | Q16850 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Cholesten 3-One SCHEMBL25996870 | 1.00 | NPC1L1 (0.79) | NPC1L1PTPN1CYP17A1MAPTKDM4E | |
| 4-Cholesten 3-One SCHEMBL1688732 | 1.00 | NPC1L1 (0.79) | NPC1L1PTPN1CYP17A1MAPTKDM4E | |
| 4-Cholesten 3-One SCHEMBL10308280 | 1.00 | NPC1L1 (0.79) | NPC1L1PTPN1CYP17A1MAPTKDM4E | |
| 4-Cholesten 3-One SCHEMBL20094570 | 1.00 | NPC1L1 (0.79) | NPC1L1PTPN1CYP17A1MAPTKDM4E | |
| 4-Cholesten 3-One SCHEMBL24151936 | 1.00 | NPC1L1 (0.79) | NPC1L1PTPN1CYP17A1MAPTKDM4E | |
| 4-Cholesten 3-One SCHEMBL23452819 | 1.00 | NPC1L1 (0.79) | NPC1L1PTPN1CYP17A1MAPTKDM4E | |
| 4-Cholesten 3-One SCHEMBL19506686 | 1.00 | NPC1L1 (0.79) | NPC1L1PTPN1CYP17A1MAPTKDM4E | |
| 4-Cholesten 3-One SCHEMBL2600424 | 1.00 | NPC1L1 (0.79) | NPC1L1PTPN1CYP17A1MAPTKDM4E | |
| 4-Cholesten 3-One SCHEMBL21176042 | 1.00 | NPC1L1 (0.79) | NPC1L1PTPN1CYP17A1MAPTKDM4E | |
| 4-Cholesten 3-One SCHEMBL601331 | 0.98 | NPC1L1 (0.79) | NPC1L1PTPN1CYP17A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4820 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743437-A1 | DIESTER LIPIDS, LIPID NANOPARTICLE CONTAINING DIESTER LIPIDS, AND FORMULATIONS THEREOF | Providence Therapeutics Holdings Inc. (CA) | 2026-05-20 | — | — | EP | claimed |
| WO-2026100273-A1 | METHOD FOR PRODUCING USEFUL SUBSTANCE, CULTURE SOLUTION FOR CULTURING ALGAE, APPARATUS FOR PRODUCING USEFUL SUBSTANCE, AND ALGAE CONTAINING USEFUL SUBSTANCE | ＮＴＴ株式会社 | 2026-05-15 | — | — | WO | claimed |
| EP-4731258-A1 | LIPID NANOPARTICLES CONTAINING DISULFIDE LIPIDS AND FORMULATIONS THEREOF | Providence Therapeutics Holdings Inc. (CA) | 2026-04-29 | — | — | EP | claimed |
| US-20260077000-A1 | METABOLIC MODULATION OF INTRATUMORAL CHOLESTEROL WITH ENGINEERED BACTERIA FOR THE TREATMENT OF CANCERS | UNIV HONG KONG BAPTIST UNIV (CN) | 2026-03-19 | — | — | US | claimed |
| EP-4707402-A1 | BIOELECTROCHEMICAL HYDROXYLATION OF SUBSTRATES USING FUNCTIONAL WATER-DEPENDENT ALKYL-HYDROXYLASE HYBRID ELECTRODES AND RESPECTIVE BIOFILM HYBRID ELECTRODES | Albert-Ludwigs-Universität Freiburg Körperschaft des öffentlichen Rechts (DE) | 2026-03-11 | — | — | EP | claimed |
| US-20260062716-A1 | LIPID NANOPARTICLE (LNP) COMPOSITION OR FORMULATION FOR NUCLEIC ACID THERAPEUTICS | POPVAX PRIVATE LTD (IN) | 2026-03-05 | — | — | US | claimed |
| US-20250313860-A1 | EXPRESSION OF EXOGENOUS PROTEINS IN DONOR PLATELETS TREATED WITH LIPID NANOPARTICLES | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2025-10-09 | — | — | US | claimed |
| US-20250269035-A1 | INHALABLE LIPID NANOPARTICLE, LIPID-CHARGED MOLECULE CONJUGATE, AND LIPID-ZWITTERIONIC MOLECULE CONJUGATE | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2025-08-28 | — | — | US | claimed |
| US-20250248939-A1 | LIPID NANOPARTICLES, NUCLEIC ACIDS, AND METHODS OF USE | CITY OF HOPE | 2025-08-07 | — | — | US | claimed |
| EP-4591859-A1 | LIPID NANOPARTICLE, PREPARATION METHOD THEREFOR, AND USE THEREOF | INSTITUTE OF CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2025-07-30 | — | — | EP | claimed |
| EP-0560983-A1 | NOVEL CHOLESTEROL OXIDASE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-09-22 | — | — | EP | claimed |
| EP-0322081-B1 | MICROBIOLOGICAL PREPARATION OF 9-ALPHA-HYDROXY-17-KETO STEROIDS | ROUSSEL-UCLAF (FR) | 1992-12-16 | — | — | EP | claimed |
| EP-0452112-A1 | Cholesterol oxidase | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-10-16 | — | — | EP | claimed |
| EP-0378395-A2 | Method of measuring cholesterol, diagnosing vascular disease, and raising HDL cholesterol levels | Maines, Robert Q. (US) | 1990-07-18 | — | — | EP | claimed |
| EP-0322081-A1 | Microbiological preparation of 9-alpha-hydroxy-17-keto steroids | ROUSSEL-UCLAF (FR) | 1989-06-28 | — | — | EP | claimed |
| US-4376733-A | Preparation of oxacycloalkenones | FRIMER ARYEH | 1983-03-15 | — | — | US | claimed |
| EP-0011235-B1 | 9-ALPHA-HYDROXY-3-OXOPREGNA-4,17(20)-DIENE-20-CARBOXYLIC ACID AND ITS METHYL ESTER AND METHODS FOR THE MICROBIOLOGICAL PRODUCTION THEREOF | MITSUBISHI KASEI CORPORATION (JP) | 1982-06-23 | — | — | EP | claimed |
| US-4093517-A | FROM MICROORGANISMS IN A YEAST EXTRACT, FERMENTATION | EASTMAN KODAK COMPANY (US) | 1978-06-06 | — | — | US | claimed |
| US-4052263-A | Production of cholesterol esterase using Nocardia cholesterolicum | EASTMAN KODAK COMPANY (US) | 1977-10-04 | — | — | US | claimed |
| US-4035237-A | CULTIVATION OF NOCARDIA IN A NUTRIENT MEDIUM CONTAINING CHOLESTEROL OR A DERIVATIVE | EASTMAN KODAK COMPANY (US) | 1977-07-12 | — | — | US | claimed |