Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.64 |
| ▸ | EYA2 | O00167 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5551303 | 0.98 | TDP1 (0.68) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL16349998 | 0.98 | TDP1 (0.62) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL12892856 | 0.95 | TDP1 (0.59) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL10051173 | 0.95 | TDP1 (0.64) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL7740566 | 0.95 | TDP1 (0.67) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL13060551 | 0.93 | TDP1 (0.68) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL14535211 | 0.92 | TDP1 (0.54) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL12392750 | 0.91 | TDP1 (0.67) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL19726617 | 0.91 | TDP1 (0.67) | TDP1BLMPMP22KDM4EALOX15 | |
| SCHEMBL5533656 | 0.88 | TDP1 (0.64) | TDP1BLMPMP22KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068443-B1 | RESIDUALIZING LINKERS AND USES THEREOF | CENTRE FOR PROBE DEV AND COMMERCIALIZATION (CA) | 2019-04-10 | — | — | EP | disclosed |
| EP-0822943-B9 | INULIN DERIVATIVES | COOPERATIE COSUN U A (NL) | 2007-02-28 | — | — | EP | disclosed |
| EP-0822943-B2 | INULIN DERIVATIVES | COOPERATIE COSUN U A (NL) | 2006-07-26 | — | — | EP | disclosed |
| EP-0822943-B1 | INULIN DERIVATIVES | COOPERATIE COSUN U A (NL) | 1999-07-14 | — | — | EP | disclosed |
| EP-0822943-A1 | INULIN DERIVATIVES | Coöperatie Cosun U.A. (NL) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996034017-A1 | INULIN DERIVATIVES | COÖPERATIE SUIKER UNIE U.A. (NL) | 1996-10-31 | — | — | WO | disclosed |