Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 18/20 | 0.56 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591272 | 0.90 | MPL (0.69) | MPL | |
| SCHEMBL5591166 | 0.86 | MPL (0.62) | MPL | |
| SCHEMBL5591079 | 0.86 | MPL (0.63) | MPL | |
| SCHEMBL5591251 | 0.83 | MPL (0.62) | MPL | |
| SCHEMBL5591372 | 0.83 | MPL (0.80) | MPL | |
| Phosphoric Acid SCHEMBL5590956 | 0.82 | MPL (0.58) | MPL | |
| Phosphoric Acid SCHEMBL5590952 | 0.82 | MPL (0.58) | MPL | |
| Phosphoric Acid SCHEMBL5590954 | 0.82 | MPL (0.58) | MPL | |
| SCHEMBL5591046 | 0.82 | MPL (0.70) | MPL | |
| SCHEMBL5591014 | 0.81 | MPL (0.69) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007004038-A1 | AMINOTHIAZOLE DERIVATIVES AS AGONISTS OF THE THROMBOPOIETIN RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-01-11 | — | — | WO | claimed |
| WO-2007004038-A1 | AMINOTHIAZOLE DERIVATIVES AS AGONISTS OF THE THROMBOPOIETIN RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-01-11 | — | — | WO | disclosed |