SCHEMBL5591995

SCHEMBL5591995

Fc1ccc(-c2cc(F)cc(COCCC3(c4ccccc4)CCNCC3)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TACR1 P25103 5/20 0.51
SLC6A4 P31645 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3604412 0.89 TACR1 (0.63) TACR1SLC6A4
SCHEMBL3592497 0.80 TACR1 (0.61) TACR1SLC6A4
SCHEMBL3597431 0.80 TACR1 (0.77) TACR1
SCHEMBL3599424 0.78 TACR1 (0.71) TACR1
SCHEMBL3596982 0.78 TACR1 (0.76) TACR1SLC6A4
SCHEMBL13404088 0.78 TACR1 (0.80) TACR1SLC6A4
SCHEMBL1388633 0.77 TACR1 (0.78) TACR1SLC6A4
Hydrochloric Acid SCHEMBL8113233 0.76 TACR1 (0.77) TACR1SLC6A4
SCHEMBL3597853 0.76 TACR1 (0.55) TACR1SLC6A4
SCHEMBL13404147 0.74 TACR1 (0.80) TACR1SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007121389-A2 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES AS NK-I AND SEROTONIN TRANSPORTER INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2007-10-25 WO disclosed