Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592020 | 0.96 | TACR1 (0.70) | TACR1 | |
| SCHEMBL5592003 | 0.89 | TACR1 (0.68) | TACR1 | |
| SCHEMBL5592161 | 0.87 | TACR1 (0.61) | TACR1 | |
| SCHEMBL3597911 | 0.86 | TACR1 (0.84) | TACR1 | |
| SCHEMBL5591974 | 0.84 | TACR1 (0.62) | TACR1 | |
| SCHEMBL3591116 | 0.81 | TACR1 (0.70) | TACR1 | |
| SCHEMBL14403903 | 0.80 | TACR1 (0.69) | TACR1 | |
| SCHEMBL3592506 | 0.80 | TACR1 (0.69) | TACR1 | |
| SCHEMBL3587228 | 0.80 | TACR1 (0.86) | TACR1 | |
| SCHEMBL3597741 | 0.79 | TACR1 (1.00) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121389-A2 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES AS NK-I AND SEROTONIN TRANSPORTER INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |