Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597398 | 0.91 | TACR1 (0.59) | TACR1 | |
| SCHEMBL5592007 | 0.90 | TACR1 (0.51) | TACR1MCHR1CYP3A4TSHRUSP2 | |
| SCHEMBL5591983 | 0.87 | TACR1 (0.67) | TACR1 | |
| SCHEMBL3599074 | 0.83 | TACR1 (0.62) | TACR1 | |
| SCHEMBL13404451 | 0.81 | TACR1 (0.61) | TACR1 | |
| SCHEMBL3597348 | 0.80 | TACR1 (0.59) | TACR1 | |
| SCHEMBL3585726 | 0.80 | TACR1 (0.62) | TACR1 | |
| SCHEMBL3591749 | 0.80 | TACR1 (0.59) | TACR1 | |
| SCHEMBL3595413 | 0.80 | TACR1 (0.45) | TACR1MCHR1 | |
| SCHEMBL3597281 | 0.77 | TACR1 (0.57) | TACR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121389-A2 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES AS NK-I AND SEROTONIN TRANSPORTER INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |