SCHEMBL5592332

SCHEMBL5592332

CC(O)C(C)C1NC(=O)NC1=O

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
RGS12 O14924 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9360332 0.83 TSHR (0.44) TSHRRGS12MEN1KMT2A
SCHEMBL9467064 0.81 TSHR (0.43) TSHRRGS12MEN1KMT2A
SCHEMBL12416737 0.80 TSHR (0.39) TSHRRGS12MEN1KMT2A
SCHEMBL12378783 0.80 TSHR (0.39) TSHRRGS12MEN1KMT2A
SCHEMBL12378787 0.80 TSHR (0.39) TSHRRGS12MEN1KMT2A
SCHEMBL23596518 0.78 TSHR (0.48) TSHRRGS12MEN1KMT2A
SCHEMBL98976 0.78 TSHR (0.48) TSHRRGS12MEN1KMT2A
SCHEMBL16597503 0.78 TSHR (0.48) TSHRRGS12MEN1KMT2A
SCHEMBL14522121 0.78 TSHR (0.40) TSHRRGS12MEN1KMT2A
SCHEMBL14522150 0.76 TSHR (0.39) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007071728-A1 HYDANTOINS WITH INSULINOTROPIC ACTION PHARMAMENS (FR) 2007-06-28 WO disclosed