Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CHKA | P35790 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2377995 | 0.85 | HRH3 (0.61) | KMT2AMEN1NAMPTPOLBHRH3 | |
| SCHEMBL20394941 | 0.85 | POLB (0.61) | NAMPTPOLBMAPK10HPGDALOX15 | |
| SCHEMBL21015832 | 0.85 | HPGD (0.57) | KMT2AMEN1NAMPTPOLBHRH3 | |
| SCHEMBL19634454 | 0.83 | KMT2A (0.67) | KMT2AMEN1NAMPTPOLBHRH3 | |
| SCHEMBL1695943 | 0.82 | HRH3 (0.55) | KMT2AMEN1NAMPTPOLBHRH3 | |
| SCHEMBL2378092 | 0.81 | NAMPT (0.54) | KMT2AMEN1NAMPTPOLBHRH3 | |
| SCHEMBL10724841 | 0.80 | POLB (0.81) | KMT2AMEN1POLBHRH3HPGD | |
| SCHEMBL3754883 | 0.80 | HRH3 (0.66) | KMT2AMEN1POLBHRH3HPGD | |
| SCHEMBL11955563 | 0.80 | HRH3 (0.66) | KMT2AMEN1POLBHRH3HPGD | |
| SCHEMBL20399607 | 0.79 | LTB4R2 (0.60) | KMT2AMEN1NAMPTPOLBHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | claimed |