Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.79 |
| ▸ | LMNA | P02545 | 5/20 | 0.79 |
| ▸ | GAA | P10253 | 2/20 | 0.79 |
| ▸ | MAPT | P10636 | 9/20 | 0.73 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.73 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24784904 | 0.88 | MEN1 (1.00) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL26134268 | 0.88 | MEN1 (1.00) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL30548101 | 0.88 | MEN1 (1.00) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL30082651 | 0.88 | MEN1 (1.00) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL19736310 | 0.88 | MEN1 (1.00) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL26134951 | 0.84 | MEN1 (0.65) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL26134959 | 0.84 | MEN1 (0.65) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL26135046 | 0.84 | MEN1 (0.65) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL20609231 | 0.83 | GAA (0.77) | MEN1KMT2ALMNAGAAMAPT | |
| SCHEMBL20609230 | 0.83 | GAA (0.77) | MEN1KMT2ALMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007074238-A2 | NOVEL N-ALK-(E)-YLIDENE-N'-PYRIMIDIN-2-YL HYDRAZINE DERIVATIVES AND USE THEREOF AS CYTOPROTECTIVE DRUGS | TROPHOS (FR) | 2007-07-05 | — | — | WO | claimed |
| WO-2007074238-A2 | NOVEL N-ALK-(E)-YLIDENE-N'-PYRIMIDIN-2-YL HYDRAZINE DERIVATIVES AND USE THEREOF AS CYTOPROTECTIVE DRUGS | TROPHOS (FR) | 2007-07-05 | — | — | WO | disclosed |