Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 16/20 | 0.51 |
| ▸ | BRAF | P15056 | 15/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551205 | 0.89 | RAF1 (0.62) | RAF1BRAFMAPK14 | |
| SCHEMBL4410361 | 0.88 | RAF1 (0.49) | RAF1BRAFMAPK14 | |
| SCHEMBL4408603 | 0.88 | RAF1 (0.48) | RAF1BRAF | |
| SCHEMBL5602980 | 0.84 | RAF1 (0.54) | RAF1BRAF | |
| SCHEMBL5623710 | 0.84 | RAF1 (0.50) | RAF1BRAFPLAU | |
| SCHEMBL15074587 | 0.82 | PLAU (0.57) | RAF1BRAFPLAUMAPK14 | |
| SCHEMBL5593026 | 0.81 | RAF1 (0.61) | RAF1BRAFMAPK14 | |
| SCHEMBL5593279 | 0.80 | RAF1 (0.50) | RAF1BRAFPLAUMAPK14 | |
| SCHEMBL4781325 | 0.80 | RAF1 (0.55) | RAF1BRAF | |
| SCHEMBL15070867 | 0.79 | PLAU (0.52) | RAF1BRAFPLAUMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |