Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 8/20 | 0.61 |
| ▸ | RAF1 | P04049 | 7/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 11/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623710 | 0.89 | RAF1 (0.50) | BRAFRAF1 | |
| SCHEMBL4541538 | 0.89 | RAF1 (0.56) | BRAFRAF1MAPK14 | |
| SCHEMBL4544153 | 0.87 | RAF1 (0.55) | BRAFRAF1MAPK14 | |
| SCHEMBL14473261 | 0.87 | RAF1 (0.56) | BRAFRAF1MAPK14 | |
| SCHEMBL14473262 | 0.86 | RAF1 (0.54) | BRAFRAF1MAPK14 | |
| SCHEMBL14473260 | 0.85 | RAF1 (0.53) | BRAFRAF1MAPK14 | |
| SCHEMBL4551205 | 0.83 | RAF1 (0.62) | BRAFRAF1MAPK14CYP3A4CYP2C9 | |
| SCHEMBL5593026 | 0.79 | RAF1 (0.61) | BRAFRAF1MAPK14CYP3A4CYP2C9 | |
| SCHEMBL4827472 | 0.79 | RAF1 (0.64) | BRAFRAF1MAPK14CYP3A4CYP2C9 | |
| SCHEMBL5592994 | 0.78 | RAF1 (0.48) | BRAFRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |