Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 5/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593123 | 0.99 | PDE2A (0.37) | BCL6PDE2APDGFRBPDGFRARPS6KA2 | |
| SCHEMBL5593148 | 0.95 | PDE2A (0.36) | PDE2ASMN1; SMN2KMT2AMBOAT4MEN1 | |
| SCHEMBL5593435 | 0.90 | PDE2A (0.37) | BCL6PDE2APDGFRBPDGFRARPS6KA2 | |
| SCHEMBL5593523 | 0.89 | PDE2A (0.39) | BCL6PDE2APDGFRBPDGFRASMN1; SMN2 | |
| SCHEMBL5593351 | 0.89 | PDE2A (0.37) | BCL6PDE2APDGFRBPDGFRARPS6KA2 | |
| SCHEMBL5593267 | 0.87 | CDK2 (0.35) | PDE2AKMT2ACDK2GSK3B | |
| SCHEMBL5593251 | 0.86 | TSHR (0.35) | PDE2AKMT2ACDK2GSK3B | |
| SCHEMBL5593414 | 0.86 | MAPT (0.38) | PDE2APDGFRBPDGFRARPS6KA2SMN1; SMN2 | |
| SCHEMBL5593450 | 0.85 | MAPT (0.39) | PDE2ARPS6KA2SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL5593060 | 0.84 | CYP1A2 (0.39) | PDE2ASMN1; SMN2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | claimed |
| WO-2007099092-A1 | SUBSTITUTED 6-PHENYL-7-AMINO[1,2,4]-TRIAZOLO[1,5-a]PYRIMIDINES AND THEIR USE FOR CONTROLLING PATHOGENIC FUNGI | BASF SE (DE) | 2007-09-07 | — | — | WO | disclosed |