Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 7/20 | 0.59 |
| ▸ | BRAF | P15056 | 7/20 | 0.59 |
| ▸ | MAPK14 | Q16539 | 13/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551704 | 0.94 | MAPK14 (0.57) | RAF1BRAFMAPK14 | |
| SCHEMBL14473141 | 0.93 | RAF1 (0.56) | RAF1BRAFMAPK14 | |
| SCHEMBL4565118 | 0.91 | RAF1 (0.56) | RAF1BRAFMAPK14 | |
| SCHEMBL4552283 | 0.91 | RAF1 (0.56) | RAF1BRAFMAPK14 | |
| SCHEMBL5593026 | 0.91 | RAF1 (0.61) | RAF1BRAFMAPK14 | |
| SCHEMBL4541475 | 0.91 | RAF1 (0.56) | RAF1BRAFMAPK14 | |
| SCHEMBL4551205 | 0.90 | RAF1 (0.62) | RAF1BRAFMAPK14 | |
| SCHEMBL4410023 | 0.90 | RAF1 (0.55) | RAF1BRAFMAPK14 | |
| SCHEMBL4409101 | 0.90 | RAF1 (0.55) | RAF1BRAFMAPK14 | |
| SCHEMBL4566569 | 0.90 | RAF1 (0.55) | RAF1BRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |