Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 8/20 | 0.59 |
| ▸ | AURKA | O14965 | 8/20 | 0.59 |
| ▸ | KDR | P35968 | 5/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14539036 | 1.00 | AURKB (0.59) | AURKBAURKAKDRFGFR1ALDH1A1 | |
| SCHEMBL14539037 | 0.87 | AURKB (0.60) | AURKBAURKAALDH1A1L3MBTL1GAA | |
| SCHEMBL14538911 | 0.86 | AURKB (0.59) | AURKBAURKAALDH1A1MEN1MAPT | |
| SCHEMBL5593766 | 0.86 | AURKB (0.59) | AURKBAURKAALDH1A1MEN1MAPT | |
| SCHEMBL14539038 | 0.86 | AURKB (0.57) | AURKBAURKAALDH1A1MAPTKMT2A | |
| SCHEMBL14538913 | 0.86 | AURKB (0.57) | AURKBAURKAALDH1A1MEN1MAPT | |
| SCHEMBL5593807 | 0.86 | AURKB (0.57) | AURKBAURKAALDH1A1MAPTKMT2A | |
| SCHEMBL5594239 | 0.84 | AURKA (0.56) | AURKBAURKAALDH1A1MEN1KMT2A | |
| SCHEMBL5594242 | 0.84 | AURKA (0.56) | AURKBAURKAALDH1A1MEN1KMT2A | |
| SCHEMBL5593988 | 0.83 | AURKB (0.55) | AURKBAURKAALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058626-A1 | INDAZOLE COMPOUNDS | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | claimed |