Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK2 | Q92630 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | IL6 | P05231 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438080 | 1.00 | DYRK2 (0.57) | DYRK2HTTALDH1A1XDHEGFR | |
| SCHEMBL3438081 | 1.00 | DYRK2 (0.57) | DYRK2HTTALDH1A1XDHEGFR | |
| SCHEMBL17077392 | 0.96 | HTT (0.58) | DYRK2HTTALDH1A1XDHEGFR | |
| SCHEMBL17077393 | 0.96 | HTT (0.58) | DYRK2HTTALDH1A1XDHEGFR | |
| SCHEMBL11845990 | 0.87 | DYRK2 (0.69) | DYRK2HTTALDH1A1XDHEGFR | |
| SCHEMBL11845989 | 0.87 | DYRK2 (0.69) | DYRK2HTTALDH1A1XDHEGFR | |
| SCHEMBL11821606 | 0.84 | DYRK2 (0.69) | DYRK2HTTALDH1A1XDHEGFR | |
| SCHEMBL11821611 | 0.84 | DYRK2 (0.69) | DYRK2HTTALDH1A1XDHEGFR | |
| SCHEMBL17459742 | 0.80 | DYRK2 (0.55) | DYRK2HTTXDHEGFRACHE | |
| SCHEMBL17459740 | 0.80 | DYRK2 (0.55) | DYRK2HTTXDHEGFRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111334-B | Chiral 2-arylmethylene cycloalkanol and asymmetric synthesis method thereof | 三峡大学 | 2020-07-28 | — | — | CN | disclosed |
| CN-109111334-A | A kind of chirality 2- aryl methylene cyclic alkanol and its method of asymmetric synthesis | 三峡大学 | 2019-01-01 | — | — | CN | disclosed |
| WO-2007072089-A1 | MGLUR5 ANTAGONISTIC CARBAMOYL-OXIME DERIVATIVES | RICHTER GEDEON VEGYÉSZETU GYÁR RT. (HU) | 2007-06-28 | — | — | WO | disclosed |