Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.39 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5594581 | 1.00 | CYP2C9 (0.47) | CYP2C9CES2CES1KMT2AALDH1A1 | |
| SCHEMBL10476370 | 0.88 | CYP2C9 (0.41) | CYP2C9CES2CES1KMT2AALDH1A1 | |
| SCHEMBL10476369 | 0.88 | CYP2C9 (0.41) | CYP2C9CES2CES1KMT2AALDH1A1 | |
| SCHEMBL5594977 | 0.75 | KMT2A (0.57) | CYP2C9KMT2AALDH1A1HTTMEN1 | |
| SCHEMBL9831143 | 0.73 | KDM4E (0.55) | CYP2C9CES2CES1KMT2AALDH1A1 | |
| SCHEMBL5798373 | 0.73 | KDM4E (0.55) | CYP2C9CES2CES1KMT2AALDH1A1 | |
| SCHEMBL5594866 | 0.73 | CAPN1 (0.60) | CYP2C9KMT2AALDH1A1HTTMEN1 | |
| SCHEMBL3557129 | 0.73 | CYP2C9 (0.43) | CYP2C9KMT2AALDH1A1HTTMEN1 | |
| SCHEMBL3557131 | 0.73 | CYP2C9 (0.43) | CYP2C9KMT2AALDH1A1HTTMEN1 | |
| SCHEMBL5594942 | 0.71 | MIF (0.51) | CYP2C9CES2CES1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | disclosed |