Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.76 |
| ▸ | MAPT | P10636 | 6/20 | 0.76 |
| ▸ | LMNA | P02545 | 3/20 | 0.76 |
| ▸ | RECQL | P46063 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310898 | 1.00 | MEN1 (0.76) | MEN1KMT2AMAPTLMNARECQL | |
| SCHEMBL27983252 | 0.90 | MEN1 (0.82) | MEN1KMT2AMAPTLMNARECQL | |
| SCHEMBL2522250 | 0.88 | MEN1 (0.74) | MEN1KMT2AMAPTLMNARECQL | |
| SCHEMBL2522254 | 0.88 | MEN1 (0.74) | MEN1KMT2AMAPTLMNARECQL | |
| SCHEMBL2886066 | 0.88 | MEN1 (0.74) | MEN1KMT2AMAPTLMNARECQL | |
| SCHEMBL2522255 | 0.88 | MEN1 (0.74) | MEN1KMT2AMAPTLMNARECQL | |
| SCHEMBL2886067 | 0.88 | MEN1 (0.74) | MEN1KMT2AMAPTLMNARECQL | |
| SCHEMBL17131948 | 0.86 | MEN1 (1.00) | MEN1KMT2AMAPTLMNARECQL | |
| SCHEMBL17131903 | 0.86 | MEN1 (1.00) | MEN1KMT2AMAPTLMNARECQL | |
| SCHEMBL9239089 | 0.85 | MEN1 (0.73) | MEN1KMT2AMAPTLMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-1778176-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-05-02 | — | — | EP | disclosed |
| WO-2005120445-A2 | MEANS FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-12-22 | — | — | WO | disclosed |