⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974702 | 1.00 | TSHR (0.46) | — | |
| SCHEMBL29823 | 0.96 | — | — | |
| SCHEMBL7775400 | 0.96 | — | — | |
| SCHEMBL25174990 | 0.92 | — | — | |
| Bromide SCHEMBL679578 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL9619502 | 0.92 | — | — | |
| Iodide SCHEMBL3466919 | 0.92 | — | — | |
| SCHEMBL16166958 | 0.92 | — | — | |
| Fluoride SCHEMBL18173294 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL320718 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114315724-A | Method for hydroamination of conjugated diene under catalysis of palladium | 中国科学院大连化学物理研究所 | 2022-04-12 | — | — | CN | claimed |
| EP-3630100-A1 | FUSED BICYCLIC COMPOUNDS | Akarna Therapeutics, Ltd. (GB) | 2020-04-08 | — | — | EP | claimed |
| WO-2018222876-A1 | FUSED BICYCLIC COMPOUNDS | AKARNA THERAPEUTICS, LTD. (GB) | 2018-12-06 | — | — | WO | claimed |
| CN-108530436-A | A kind of pyrazole compound and its preparation method and application | 黄传满 | 2018-09-14 | — | — | CN | claimed |
| CN-102482195-B | Tetraarylborate process for producing substituted biphenyls | BAYER CROPSCIENCE AG | 2015-04-01 | — | — | CN | claimed |
| CN-104370898-A | Imidazo[1,2-a]pyridine compound, preparation method and applications thereof | HUANG CHUANMAN | 2015-02-25 | — | — | CN | claimed |
| CN-104341407-A | Quinazoline compounds, preparation method and applications thereof | HUANG CHUANMAN | 2015-02-11 | — | — | CN | claimed |
| CN-104250245-A | Synthesis and application of 1-(5-(2-aminobenzo[d]oxazole-5-yl)-1, 3, 4-thiadiazole-2-yl)-3-(2-fluoro-5-methyl phenyl)urea | KEJIE BIO SUZHOU PHARMACEUTICALS CO LTD | 2014-12-31 | — | — | CN | claimed |
| CN-104250250-A | 4-aromatic aminopyrimidine compound and anti-tumor use thereof | KEJIE BIO SUZHOU PHARMACEUTICALS CO LTD | 2014-12-31 | — | — | CN | claimed |
| CN-104230913-A | Piperazine-substituted quinazoline compound and use thereof | HUANG CHUANMAN | 2014-12-24 | — | — | CN | claimed |
| CN-104177346-A | Quinazoline compound and use thereof | KEJIE BIO SUZHOU PHARMACEUTICALS CO LTD | 2014-12-03 | — | — | CN | claimed |
| CN-104119343-A | 2-trifluoromethyl thiadiazole compound and application thereof | KEJIE BIO SUZHOU PHARMACEUTICALS CO LTD | 2014-10-29 | — | — | CN | claimed |
| CN-104098574-A | Azetidine substituted pyrimidine compounds and use thereof | KEJIE BIO SUZHOU PHARMACEUTICALS CO LTD | 2014-10-15 | — | — | CN | claimed |
| CN-104072499-A | Piperazine substituted pyrimidine compounds and applications thereof | HUANG CHUANMAN | 2014-10-01 | — | — | CN | claimed |
| CN-103242321-A | Benzylpiperazine compound and anti-tumor application thereof | KEJIE BIO SUZHOU PHARMACEUTICAL CO LTD | 2013-08-14 | — | — | CN | claimed |
| CN-1775738-A | Arylamine hole transport material using binaphthalene as backbone and its synthesizing method | UNIV NANCHANG (CN) | 2006-05-24 | — | — | CN | claimed |
| EP-4366834-A1 | COMPOUNDS FOR TARGETING DEGRADATION OF IRAK4 PROTEINS | Biogen MA Inc. (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2023210792-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE OF BOTH OF FOREGOING | 日本農薬株式会社 | 2023-11-02 | — | — | WO | disclosed |
| CN-1775738-A | Arylamine hole transport material using binaphthalene as backbone and its synthesizing method | UNIV NANCHANG (CN) | 2006-05-24 | — | — | CN | disclosed |
| WO-2005110414-A2 | HIV INTEGRASE INHIBITORS | MERCK & CO., INC. (US) | 2005-11-24 | — | — | WO | disclosed |