SCHEMBL5595682

SCHEMBL5595682

NCCCCC1CNCCN1CCCCN

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.41
RAD52 P43351 2/20 0.38
ZDHHC9 Q9Y397 1/20 0.33
POLB P06746 1/20 0.33
GLA P06280 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MITF O75030 1/20 0.31
MAPK1 P28482 1/20 0.30
APAF1 O14727 1/20 0.30
IDE P14735 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11806053 0.98 TAAR1 (0.40) TAAR1RAD52ZDHHC9POLBGLA
SCHEMBL4944745 0.92 TAAR1 (0.48) TAAR1RAD52
SCHEMBL224089 0.91 TAAR1 (0.42) TAAR1RAD52TDP1MITFAPAF1
Formaldehyde SCHEMBL7057305 0.89 TAAR1 (0.36) TAAR1RAD52
Piperazine SCHEMBL28220092 0.88 TAAR1 (0.40) TAAR1MITF
SCHEMBL28806944 0.88 TAAR1 (0.39) TAAR1TDP1MITFAPAF1IDE
SCHEMBL10385631 0.87 CA1 (0.39) TAAR1TDP1
SCHEMBL11208673 0.83 TAAR1 (0.38) TAAR1POLB
SCHEMBL250854 0.83 TAAR1 (0.53) TAAR1ZDHHC9
SCHEMBL4446755 0.83 TAAR1 (0.53) TAAR1ZDHHC9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115720598-A Composition for electroplating copper on cobalt seed 巴斯夫欧洲公司 2023-02-28 CN disclosed
CN-115182004-A Composition for metal plating comprising an inhibiting agent for void-free filling 巴斯夫欧洲公司 2022-10-14 CN disclosed
CN-110100048-B Composition for metal plating comprising an inhibiting agent for void-free filling 巴斯夫欧洲公司 2022-06-21 CN disclosed
EP-3021834-A1 HEAT-STABLE DRY POWDER PHARMACEUTICAL COMPOSITIONS AND METHODS MannKind Corporation (US) 2016-05-25 EP disclosed
WO-2015010092-A1 HEAT-STABLE DRY POWDER PHARMACEUTICAL COMPOSITIONS AND METHODS MANNKIND CORPORATION (US) 2015-01-22 WO disclosed
EP-1809288-A1 USE OF 1,4-BIS (3-AMINOALKYL) PIPERAZINE DERIVATIVES IN THE TREATMENT OF NEURODEGENERATIVE DISEASES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2007-07-25 EP disclosed
WO-2006051489-A1 USE OF 1,4-BIS (3-AMINOALKYL) PIPERAZINE DERIVATIVES IN THE TREATMENT OF NEURODEGENERATIVE DISEASES INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2006-05-18 WO disclosed
EP-0032076-B1 PROCESS FOR IMPROVING THE COMPATIBILITY OF OILS AND FILLERS IN RUBBER COMPOSITIONS RHONE-POULENC CHIMIE DE BASE (FR) 1985-06-12 EP disclosed
EP-0076197-A1 Additive for the reinforcement of polymers and in particular elastomers with mineral charges RHONE-POULENC CHIMIE DE BASE (FR) 1983-04-06 EP disclosed
EP-0034970-A1 Process for coupling an elastomer and a filler, especially on the basis of a silicium composite RHONE-POULENC CHIMIE DE BASE (FR) 1981-09-02 EP disclosed
EP-0032076-A2 Process for improving the compatibility of oils and fillers in rubber compositions RHONE-POULENC CHIMIE DE BASE (FR) 1981-07-15 EP disclosed