SCHEMBL5595875

SCHEMBL5595875

CCCCc1cc(CCCC)c(O)c(P(c2cc(CCCC)cc(CCCC)c2O)c2c(C)cc(C)cc2C)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.42
NPC1 O15118 2/20 0.42
MAPK1 P28482 2/20 0.42
RAB9A P51151 2/20 0.42
HPGD P15428 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
PTGS2 P35354 6/20 0.37
CYP3A4 P08684 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
TYR P14679 1/20 0.34
MAOA P21397 1/20 0.34
ALOX5 P09917 4/20 0.33
SKP2 Q13309 1/20 0.33
TP53 P04637 1/20 0.32
POLB P06746 1/20 0.32
NFKB1 P19838 1/20 0.32
NFKB2 Q00653 1/20 0.32
RELA Q04206 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5596189 0.91 HTT (0.38) HTTNPC1MAPK1RAB9AHPGD
SCHEMBL5596850 0.88 NPC1 (0.45) HTTNPC1MAPK1RAB9AHPGD
SCHEMBL5596919 0.79 NPC1 (0.46) HTTNPC1MAPK1RAB9AHPGD
SCHEMBL5596579 0.77 NPC1 (0.44) HTTNPC1MAPK1RAB9AHPGD
SCHEMBL5596049 0.77 HPGD (0.39) HTTNPC1MAPK1RAB9AHPGD
SCHEMBL1022711 0.76 NPC1 (0.55) HTTNPC1MAPK1RAB9AHPGD
SCHEMBL5596010 0.76 NPC1 (0.43) HTTNPC1MAPK1RAB9AHPGD
SCHEMBL5596669 0.76 NPC1 (0.43) HTTNPC1MAPK1RAB9AHPGD
SCHEMBL5596557 0.76 NPC1 (0.43) HTTNPC1MAPK1RAB9AHPGD
SCHEMBL201692 0.76 NPC1 (0.57) HTTNPC1MAPK1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7279537-B2 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-10-09 US disclosed
US-20060229195-A1 Transition metal complexes and polymerization catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-10-12 US disclosed
EP-1557423-A1 TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS Sumitomo Chemical Company, Limited (JP) 2005-07-27 EP disclosed