Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 16/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2354674 | 0.81 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL2351732 | 0.78 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| Hydrochloric Acid SCHEMBL9260352 | 0.78 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL1041969 | 0.77 | CYP19A1 (0.76) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL1912921 | 0.76 | CYP19A1 (0.74) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL2351179 | 0.76 | CYP19A1 (0.73) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL2354504 | 0.74 | CYP19A1 (0.70) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| Dexfadrostat SCHEMBL685516 | 0.73 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| S-Fadrozole SCHEMBL13449014 | 0.73 | CYP19A1 (1.00) | CYP19A1CYP11B2CYP11B1KCNH2 | |
| SCHEMBL2350719 | 0.72 | CYP19A1 (0.69) | CYP19A1CYP11B2CYP11B1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1381431-B1 | AROMATASE INHIBITION TO ENHANCE IMPLANTATION RATE | ARES TRADING SA (CH) | 2007-06-06 | — | — | EP | disclosed |