Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiobenzoic Acid SCHEMBL7714480 | 0.92 | TSHR (0.50) | TSHRBCL2BCL2L1CYP2D6CYP2C19 | |
| SCHEMBL8560558 | 0.88 | TSHR (0.50) | TSHRBCL2BCL2L1CYP2D6CYP2C19 | |
| SCHEMBL28883194 | 0.84 | TSHR (0.54) | TSHRSCN1ASCN2ASCN3ACA1 | |
| SCHEMBL7897721 | 0.83 | TSHR (0.49) | TSHRBCL2BCL2L1CYP2D6CYP2C19 | |
| SCHEMBL6270999 | 0.83 | TSHR (0.49) | TSHRBCL2BCL2L1CYP2D6CYP2C19 | |
| SCHEMBL11517264 | 0.83 | TSHR (0.49) | TSHRBCL2BCL2L1CYP2D6CYP2C19 | |
| SCHEMBL7020791 | 0.79 | TSHR (0.49) | TSHRBCL2BCL2L1CYP2D6CYP2C19 | |
| SCHEMBL11819720 | 0.79 | MEN1 (0.46) | HTR2AALDH1A1MAPTBLM | |
| SCHEMBL28867831 | 0.79 | TSHR (0.42) | TSHRCYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL1247034 | 0.78 | TSHR (0.61) | TSHRBCL2BCL2L1CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102440245-A | O- (2-chloro) benzylthio benzoic acid preparation, preparation method and application | UNIV NANKAI | 2012-05-09 | — | — | CN | claimed |
| CN-101700012-A | O-(4-chloro) benzylthio benzoic acid preparation and preparation method as well as application | UNIV NANKAI | 2010-05-05 | — | — | CN | claimed |
| EP-1136521-B1 | Process for preparing an ocular lens material having hydrophilic surface | MENICON CO LTD (JP) | 2007-02-21 | — | — | EP | claimed |
| US-5739228-A | Polymerization using thionoester compounds as chain transfer agents | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1998-04-14 | — | — | US | claimed |
| CN-110997882-A | Lubricating composition containing self-assembling polymethacrylate block copolymer and ethylene- α -olefin copolymer | 路博润公司 | 2020-04-10 | — | — | CN | disclosed |
| CN-103355294-A | O-(4-fluorine) thiophenyl benzoic acid water dispersible granule and preparation method thereof | UNIV NANKAI | 2013-10-23 | — | — | CN | disclosed |
| CN-102731354-A | Preparation and plant growth-regulating activity of water-oil soluble o-(4-chloro) benzylthio-benzoate derivatives | UNIV NANKAI | 2012-10-17 | — | — | CN | disclosed |
| CN-102440245-A | O- (2-chloro) benzylthio benzoic acid preparation, preparation method and application | UNIV NANKAI | 2012-05-09 | — | — | CN | disclosed |
| CN-102440245-A | O- (2-chloro) benzylthio benzoic acid preparation, preparation method and application | UNIV NANKAI | 2012-05-09 | — | — | CN | disclosed |
| CN-101700012-A | O-(4-chloro) benzylthio benzoic acid preparation and preparation method as well as application | UNIV NANKAI | 2010-05-05 | — | — | CN | disclosed |
| EP-0550111-B1 | 2-Saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and pharmaceutical compositions containing them | SANOFI SA (FR) | 1999-04-14 | — | — | EP | disclosed |
| US-5856349-A | 2-Saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | SANOFI (FR) | 1999-01-05 | — | — | US | disclosed |
| US-5250696-A | Treatment of degenerative diseases | STERLING WINTHROP INC. (US) | 1993-10-05 | — | — | US | disclosed |
| EP-0550112-A1 | 2-Saccharinylmethyl aryl and aryloxy acetates useful as proteolytic enzyme inhibitors and pharmaceutical compositions contaning them | STERLING WINTHROP INC. (US) | 1993-07-07 | — | — | EP | disclosed |
| EP-0550111-A1 | 2-Saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors and pharmaceutical compositions containing them | STERLING WINTHROP INC. (US) | 1993-07-07 | — | — | EP | disclosed |
| EP-0549073-A1 | Novel 2-saccharinylmethyl and 4,5,6,7-tetrahydro-2-saccharinylmethyl phosphates, phosphonates and phosphinates useful as proteolytic enzyme inhibitors and compositions and method of use thereof | STERLING WINTHROP INC. (US) | 1993-06-30 | — | — | EP | disclosed |
| US-5187173-A | Degenerative diseases such as emphysema, rheumatoid arthritis, pancreatitis, cyctic fibrosis and skin disorders | STERLING WINTHROP INC. (US) | 1993-02-16 | — | — | US | disclosed |
| US-5128339-A | Emphysema, rheumatoid arthritis, pancreatitis | STERLING WINTHROP INC. (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0483928-A1 | 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use | STERLING WINTHROP INC. (US) | 1992-05-06 | — | — | EP | disclosed |
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |