Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 20/20 | 0.46 |
| ▸ | CSF1R | P07333 | 17/20 | 0.46 |
| ▸ | KDR | P35968 | 15/20 | 0.45 |
| ▸ | FLT3 | P36888 | 6/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598353 | 0.85 | PDGFRB (0.46) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL5598590 | 0.84 | CSF1R (0.43) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL5599118 | 0.82 | PDGFRB (0.52) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2173090 | 0.81 | PDGFRB (0.65) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL5598961 | 0.81 | PDGFRB (0.54) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL5598778 | 0.81 | PDGFRB (0.53) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2176217 | 0.80 | PDGFRB (0.67) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL5598739 | 0.80 | PDGFRB (0.74) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL5610673 | 0.79 | PDGFRB (0.49) | PDGFRBCSF1RKDRFLT3MET | |
| SCHEMBL2176117 | 0.79 | PDGFRB (0.53) | PDGFRBCSF1RKDRFLT3MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113548-A1 | NAPHTHYRIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |