Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 17/20 | 0.50 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 7/20 | 0.49 |
| ▸ | BCHE | P06276 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14457991 | 0.88 | CNR2 (0.54) | CNR2CNR1BCHEACHEOPRM1 | |
| SCHEMBL5598200 | 0.88 | CNR2 (0.65) | CNR2CNR1BCHEACHEOPRM1 | |
| SCHEMBL5598325 | 0.87 | CNR2 (0.70) | CNR2CNR1BCHEACHEOPRM1 | |
| SCHEMBL5632327 | 0.87 | CNR2 (0.55) | CNR2CNR1BCHEACHEOPRM1 | |
| SCHEMBL5598830 | 0.86 | CNR2 (0.65) | CNR2CNR1BCHEACHE | |
| SCHEMBL5598672 | 0.86 | CNR2 (0.67) | CNR2CNR1 | |
| SCHEMBL5598424 | 0.85 | CNR2 (0.68) | CNR2CNR1 | |
| SCHEMBL5598476 | 0.84 | CNR2 (0.71) | CNR2CNR1 | |
| SCHEMBL5598448 | 0.84 | CNR2 (0.68) | CNR2CNR1 | |
| SCHEMBL5598293 | 0.83 | CNR2 (0.69) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091950-A1 | BENZIMIDAZOLES AND IMIDAZOPYRIDINES USEFUL IN THE TREATMENT OF DISEASES OR DISORDERS ASSOCIATED WITH CANNABINOID RECEPTOR 2 (CB2) SUCH AS PAIN | ASTRAZENECA AB (SE) | 2007-08-16 | — | — | WO | disclosed |
| WO-2007091950-A1 | BENZIMIDAZOLES AND IMIDAZOPYRIDINES USEFUL IN THE TREATMENT OF DISEASES OR DISORDERS ASSOCIATED WITH CANNABINOID RECEPTOR 2 (CB2) SUCH AS PAIN | ASTRAZENECA AB (SE) | 2007-08-16 | — | — | WO | disclosed |