Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526308 | 1.00 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL19566738 | 1.00 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL19628851 | 0.95 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9764407 | 0.94 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9763692 | 0.94 | TSHR (0.54) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9763752 | 0.94 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9221742 | 0.92 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL9195450 | 0.92 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL10005277 | 0.90 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL14559754 | 0.88 | TSHR (0.45) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123656-A1 | Polyolefin graft copolymer | KANEKA CORPORATION (JP) | 2007-05-31 | — | — | US | disclosed |
| US-20060223943-A1 | Polyolefin graft copolymer obtained by using late transition metal complex coordination polymerization catalyst and method for producing same | KANEKA CORPORATION (JP) | 2006-10-05 | — | — | US | disclosed |
| EP-1671985-A1 | POLYOLEFIN GRAFT COPOLYMER | KANEKA CORPORATION (JP) | 2006-06-21 | — | — | EP | disclosed |
| EP-1619214-A1 | POLYOLEFIN GRAFT COPOLYMER OBTAINED BY USING LATE TRANSITION METAL COMPLEX COORDINATION POLYMERIZATION CATALYST AND METHOD FOR PRODUCING SAME | KANEKA CORPORATION (JP) | 2006-01-25 | — | — | EP | disclosed |