Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 20/20 | 0.83 |
| ▸ | CSF1R | P07333 | 19/20 | 0.83 |
| ▸ | KDR | P35968 | 15/20 | 0.83 |
| ▸ | FLT3 | P36888 | 8/20 | 0.83 |
| ▸ | FLT4 | P35916 | 2/20 | 0.66 |
| ▸ | MET | P08581 | 1/20 | 0.54 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2175255 | 0.91 | PDGFRB (0.85) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL2173186 | 0.89 | PDGFRB (1.00) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL2173586 | 0.87 | PDGFRB (1.00) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL2174486 | 0.86 | PDGFRB (0.85) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL2175741 | 0.86 | PDGFRB (0.85) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL5598426 | 0.86 | PDGFRB (0.75) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL2176706 | 0.85 | PDGFRB (0.83) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL2175444 | 0.85 | PDGFRB (0.84) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL2173638 | 0.85 | PDGFRB (0.84) | PDGFRBCSF1RKDRFLT3FLT4 | |
| SCHEMBL5591884 | 0.85 | PDGFRB (0.70) | PDGFRBCSF1RKDRFLT3FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007113548-A1 | NAPHTHYRIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2007-10-11 | — | — | WO | disclosed |