Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 1/20 | 0.69 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.68 |
| ▸ | OSBP | P22059 | 3/20 | 0.64 |
| ▸ | USP2 | O75604 | 2/20 | 0.64 |
| ▸ | RORC | P51449 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.64 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.64 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.57 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GBA1 | P04062 | 2/20 | 0.55 |
| ▸ | UGCG | Q16739 | 2/20 | 0.55 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.55 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.55 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.55 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598712 | 1.00 | POLA1 (0.69) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL9446914 | 0.93 | POLA1 (0.70) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL14138204 | 0.93 | POLA1 (0.70) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL12154332 | 0.93 | POLA1 (0.70) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL11288161 | 0.93 | POLA1 (0.70) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL17270372 | 0.93 | POLA1 (0.70) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL14097581 | 0.93 | POLA1 (0.70) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL18904679 | 0.93 | POLA1 (0.70) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL5343790 | 0.92 | POLA1 (0.69) | POLA1CYP46A1OSBPUSP2RORC | |
| SCHEMBL5343788 | 0.92 | POLA1 (0.69) | POLA1CYP46A1OSBPUSP2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3914497-B2 | — | — | 2007-05-16 | — | — | JP | claimed |
| EP-1328190-B1 | TEMPERATURE MEASURING BALLOON | BOSTON SCIENT LTD (BB) | 2004-12-29 | — | — | EP | claimed |
| JP-2004510480-A | — | — | 2004-04-08 | — | — | JP | claimed |
| EP-1328190-A2 | TEMPERATURE MEASURING BALLOON | Boston Scientific Limited (BB) | 2003-07-23 | — | — | EP | claimed |
| US-6450971-B1 | Temperature measuring balloon | SCIMED LIFE SYSTEMS, INC. | 2002-09-17 | — | — | US | claimed |
| WO-2002028276-A2 | TEMPERATURE MEASURING BALLOON | SCIMED LIFE SYSTEMS, INC. (US) | 2002-04-11 | — | — | WO | claimed |
| US-7022331-B2 | Thermochromic/photochromic cosmetic compositions | Theisen, Lyle (US) | 2006-04-04 | — | — | US | disclosed |
| EP-1328190-B1 | TEMPERATURE MEASURING BALLOON | BOSTON SCIENT LTD (BB) | 2004-12-29 | — | — | EP | disclosed |
| US-20020192247-A1 | Thermochromic/photochromic cosmetic compositions | THEISEN LYLE (US) | 2002-12-19 | — | — | US | disclosed |
| US-6450971-B1 | Temperature measuring balloon | SCIMED LIFE SYSTEMS, INC. | 2002-09-17 | — | — | US | disclosed |
| EP-0927753-A1 | Liquid crystal dispersed polymer electrooptical films having reverse morphology | Sniaricerche S.C.P.A. (IT) | 1999-07-07 | — | — | EP | disclosed |
| US-4064872-A | Temperature measuring device of a liquid crystal laminate | ASHLEY-BUTLER, INC. (US) | 1977-12-27 | — | — | US | disclosed |