Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011787 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2CA14CA12ABCB1CA7 | |
| SCHEMBL5511881 | 0.80 | — | — | |
| SCHEMBL2159081 | 0.80 | — | — | |
| SCHEMBL5518792 | 0.80 | — | — | |
| SCHEMBL13946795 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2CA14CA12ABCB1CA7 | |
| SCHEMBL784551 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2CA14CA12ABCB1CA7 | |
| SCHEMBL16126140 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2CA14CA12ABCB1CA7 | |
| SCHEMBL14116704 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2CA14CA12ABCB1CA7 | |
| SCHEMBL16126141 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2CA14CA12ABCB1CA7 | |
| SCHEMBL7123594 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813302-A | Substituted tetrahydrofuran-2-carboxamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-114945566-A | Substituted tetrahydrofurans as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2022-08-26 | — | — | CN | disclosed |
| EP-1501777-A4 | DIRECT, ENANTIOSELECTIVE ALDOL COUPLING OF ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INST OF TECHN (US) | 2007-03-28 | — | — | EP | disclosed |
| EP-1501777-A1 | DIRECT, ENANTIOSELECTIVE ALDOL COUPLING OF ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003089396-A1 | DIRECT, ENANTIOSELECTIVE ALDOL COUPLING OF ALDEHYDES USING CHIRAL ORGANIC CATALYSTS | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-10-30 | — | — | WO | disclosed |
| US-4448980-A | BY CARBONYLATION WITH BIFLUORIDE CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-15 | — | — | US | disclosed |