SCHEMBL5599202

SCHEMBL5599202

CC(Br)OC(=O)Cc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.73
CES2 O00748 2/20 0.52
CES1 P23141 2/20 0.52
ALDH1A1 P00352 1/20 0.52
MAPK1 P28482 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
PAM P19021 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49
KLK7 P49862 4/20 0.48
AKR1B1 P15121 1/20 0.47
CYP19A1 P11511 1/20 0.46
FAAH O00519 1/20 0.45
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7320807 0.86 TSHR (0.69) TSHRCES2CES1ALDH1A1MAPK1
SCHEMBL873430 0.85 TSHR (1.00) TSHRCES2CES1ALDH1A1MAPK1
SCHEMBL27883126 0.83 TSHR (0.96) TSHRCES2CES1ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL27332250 0.83 TSHR (0.96) TSHRCES2CES1ALDH1A1MAPK1
SCHEMBL28134676 0.83 TSHR (0.76) TSHRCES2CES1ALDH1A1MAPK1
SCHEMBL27120274 0.83 TSHR (0.76) TSHRCES2CES1ALDH1A1MAPK1
SCHEMBL12412855 0.81 TSHR (0.73) TSHRCES2CES1ALDH1A1MAPK1
SCHEMBL5761203 0.81 TSHR (0.73) TSHRCES2CES1ALDH1A1MAPK1
SCHEMBL12412853 0.81 TSHR (0.73) TSHRCES2CES1ALDH1A1MAPK1
SCHEMBL28182067 0.81 TSHR (0.73) TSHRCES2CES1ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114702630-A Lignin-based polymer and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2022-07-05 CN claimed
CN-112876592-B Ultra-narrow molecular weight distribution polymethacrylate polymer and preparation method thereof 苏州大学 2022-03-01 CN claimed
CN-112876592-A Ultra-narrow molecular weight distribution polymethacrylate polymer and preparation method thereof 苏州大学 2021-06-01 CN claimed
CN-108997524-B Method for preparing copolymer based on in-situ styrene release method 苏州大学 2020-07-07 CN claimed
CN-108752510-A Without iron catalysis AGET ATRP systems and polymerization under the conditions of ligand in a kind of biomass-based solvent 安徽工程大学 2018-11-06 CN claimed
CN-118325112-A Photocatalyst material based on Salen matrix unit and preparation method thereof, and application of photocatalyst material in polymerization inhibitor free radical polymerization 合肥工业大学 2024-07-12 CN disclosed
CN-115521404-A Furanvinylalcohol elastomer based on straw and preparation method thereof 中国科学院长春应用化学研究所 2022-12-27 CN disclosed
CN-114702630-A Lignin-based polymer and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2022-07-05 CN disclosed
CN-112876592-B Ultra-narrow molecular weight distribution polymethacrylate polymer and preparation method thereof 苏州大学 2022-03-01 CN disclosed
CN-113667437-A Preparation method of epoxy underfill with excellent flow property 烟台德邦科技股份有限公司 2021-11-19 CN disclosed
CN-112876592-A Ultra-narrow molecular weight distribution polymethacrylate polymer and preparation method thereof 苏州大学 2021-06-01 CN disclosed
CN-108997524-B Method for preparing copolymer based on in-situ styrene release method 苏州大学 2020-07-07 CN disclosed
CN-102947300-B Alkaloid amino ester derivative and pharmaceutical composition thereof 奇斯药制品公司 2016-09-21 CN disclosed
CN-102947298-B Alkaloid aminoester derivatives and pharmaceutical compositions thereof CHIESI FARMACEUTICI S.P.A. (IT) 2016-03-02 CN disclosed
CN-105246890-A Pyrrolo[2, 3-b]pyridine cdk9 kinase inhibitors ABBVIE INC 2016-01-13 CN disclosed
CN-102947299-B Alkaloid aminoester derivatives and pharmaceutical compositions thereof CHIESI FARMA SPA 2015-07-15 CN disclosed
CN-102159200-B Novel sulphur containing lipids for use as food supplement or as medicament PRONOVA BIOPHARMA NORGE AS 2015-06-24 CN disclosed
CN-102264734-B Alkaloid aminoester derivatives and medicinal composition thereof CHIESI FARMA SPA 2015-06-17 CN disclosed
EP-1857471-B1 POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER MITSUI CHEMICALS INC (JP) 2013-04-24 EP disclosed
EP-1857471-A1 POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER Mitsui Chemicals, Inc. (JP) 2007-11-21 EP disclosed