SCHEMBL5599217

SCHEMBL5599217

CC(C)NC1CC(C)(C)CC(C)(CN)C1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
PBK Q96KB5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16295541 0.81 TSHR (0.39) TSHRPBK
SCHEMBL118304 0.81 TSHR (0.41) TSHR
SCHEMBL8421973 0.80 TSHR (0.31) TSHR
SCHEMBL1832852 0.79 TSHR (0.38) TSHRPBK
SCHEMBL8499269 0.79 TSHR (0.38) TSHRPBK
Ammonia Solution, Strong SCHEMBL19024280 0.79 TSHR (0.40) TSHR
SCHEMBL3013067 0.78 TSHR (0.33) TSHR
SCHEMBL4641340 0.78 TSHR (0.37) TSHRPBK
SCHEMBL22212777 0.78 TSHR (0.37) TSHRPBK
SCHEMBL14810151 0.78 TSHR (0.31) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5919568-A A CURABLE POLYURETHANE COATINGS COMPRISING A PULVERULENT POLYISOCYANATE AND ORGANIC POLYHYDROXY COMPONENT; FREE OF BLOCKING AGENT HUELS AKTIENGESELLSCHAFT (DE) 1999-07-06 US claimed
EP-0780416-A1 Powder coating and its use for thermoresistant substrates HÜLS AKTIENGESELLSCHAFT (DE) 1997-06-25 EP claimed
EP-1404732-B1 SYNERGISTIC AMINE CHAIN-EXTENDERS IN POLYUREA SPRAY ELASTOMERS HUNTSMAN SPEC CHEM CORP (US) 2007-07-25 EP disclosed
US-20060160980-A1 Synergistic amine chain extenders in polyurea spray elestomers HUNTSMAN PETROCHEMICAL CORPORATION (US) 2006-07-20 US disclosed
US-7078475-B2 Synergistic amine chain-extenders in polyurea spray elastomers HUNTSMAN PETROCHEMICAL CORPORATION (US) 2006-07-18 US disclosed
EP-1404732-A4 SYNERGISTIC AMINE CHAIN-EXTENDERS IN POLYUREA SPRAY ELASTOMERS HUNTSMAN SPEC CHEM CORP (US) 2004-11-03 EP disclosed
US-20040171786-A1 FROM ISOCYANATE, POLYOL AND AMINE HUNTSMAN PETROCHEMICAL CORPORATION (N/K/A HUNTSMAN PETROCHEMICAL LLC) 2004-09-02 US disclosed
EP-1404732-A1 SYNERGISTIC AMINE CHAIN-EXTENDERS IN POLYUREA SPRAY ELASTOMERS HUNTSMAN PETROCHEMICAL CORPORATION (US) 2004-04-07 EP disclosed
WO-2002102869-A1 SYNERGISTIC AMINE CHAIN-EXTENDERS IN POLYUREA SPRAY ELASTOMERS HUNTSMAN PETROCHEMICAL CORPORATION (US) 2002-12-27 WO disclosed
US-5919568-A A CURABLE POLYURETHANE COATINGS COMPRISING A PULVERULENT POLYISOCYANATE AND ORGANIC POLYHYDROXY COMPONENT; FREE OF BLOCKING AGENT HUELS AKTIENGESELLSCHAFT (DE) 1999-07-06 US disclosed
EP-0780416-A1 Powder coating and its use for thermoresistant substrates HÜLS AKTIENGESELLSCHAFT (DE) 1997-06-25 EP disclosed