Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | GMNN | O75496 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5708805 | 0.86 | KMT2A (0.87) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL14640683 | 0.86 | MAPT (0.72) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL31657800 | 0.86 | KMT2A (0.87) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL5708740 | 0.83 | KMT2A (0.78) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL5708706 | 0.83 | KMT2A (0.78) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL5708800 | 0.83 | MAPT (0.71) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL5708910 | 0.83 | MAPT (0.71) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL5599420 | 0.83 | MAPT (0.67) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL31657812 | 0.83 | MEN1 (0.67) | KMT2AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL5599355 | 0.83 | MAPT (0.67) | KMT2AMAPTALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011290-A1 | Bronchorelaxing agents based on indol- and isoquinoline derivatives | RESPIRATORIUS AB (SE) | 2007-01-25 | — | — | WO | disclosed |