Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789781 | 0.95 | ESR2 (0.66) | NR1H2ESR2PTPN1NPC1RAB9A | |
| SCHEMBL7017461 | 0.93 | NPC1 (0.58) | NR1H2ESR2PTPN1NPC1RAB9A | |
| SCHEMBL6393284 | 0.92 | PTPN1 (0.64) | NR1H2ESR2PTPN1NPC1RAB9A | |
| SCHEMBL18423515 | 0.90 | PTPN1 (0.55) | NR1H2ESR2PTPN1NPC1RAB9A | |
| SCHEMBL8149885 | 0.89 | NPC1 (0.58) | NR1H2ESR2PTPN1NPC1RAB9A | |
| SCHEMBL29586676 | 0.86 | NR1H2 (0.69) | NR1H2ESR2PTPN1NPC1RAB9A | |
| SCHEMBL21326142 | 0.86 | NR1H2 (0.69) | NR1H2ESR2PTPN1NPC1RAB9A | |
| SCHEMBL3294449 | 0.85 | NR1H2 (0.71) | NR1H2ESR2PTPN1NPC1RAB9A | |
| SCHEMBL21470977 | 0.85 | NR1H2 (0.67) | NR1H2ESR2PTPN1NPC1RAB9A | |
| SCHEMBL31174273 | 0.84 | NR1H2 (0.66) | NR1H2ESR2NPC1RAB9AIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011290-A1 | Bronchorelaxing agents based on indol- and isoquinoline derivatives | RESPIRATORIUS AB (SE) | 2007-01-25 | — | — | WO | disclosed |