SCHEMBL5600895

SCHEMBL5600895

CCCCCCCCCCCc1c[nH]nn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.47
CYP19A1 P11511 6/20 0.37
S1PR1 P21453 1/20 0.36
HRH4 Q9H3N8 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
ALDH1A1 P00352 3/20 0.35
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
MIF P14174 1/20 0.35
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5023555 1.00 KCNH2 (0.47) KCNH2CYP19A1S1PR1HRH4HRH3
SCHEMBL5603669 1.00 KCNH2 (0.47) KCNH2CYP19A1S1PR1HRH4HRH3
SCHEMBL245886 1.00 KCNH2 (0.47) KCNH2CYP19A1S1PR1HRH4HRH3
SCHEMBL245127 1.00 KCNH2 (0.47) KCNH2CYP19A1S1PR1HRH4HRH3
SCHEMBL16196855 1.00 KCNH2 (0.47) KCNH2CYP19A1S1PR1HRH4HRH3
SCHEMBL5601502 1.00 KCNH2 (0.47) KCNH2CYP19A1S1PR1HRH4HRH3
SCHEMBL243705 1.00 KCNH2 (0.47) KCNH2CYP19A1S1PR1HRH4HRH3
SCHEMBL628308 0.98 KCNH2 (0.44) KCNH2CYP19A1S1PR1HRH4HRH3
Hydrochloric Acid SCHEMBL27830421 0.96 KCNH2 (0.42) KCNH2CYP19A1S1PR1HRH4HRH3
SCHEMBL9634220 0.90 EPHX2 (0.41) KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed