Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 2/20 | 0.35 |
| ▸ | LDHB | P07195 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4907871 | 0.83 | SLC6A4 (0.40) | FFAR1SLC6A4HRH3L3MBTL1CACNA1B | |
| SCHEMBL5924545 | 0.79 | HRH3 (0.43) | FFAR1SLC6A4HRH3L3MBTL1MAPT | |
| SCHEMBL5599142 | 0.75 | FFAR1 (0.52) | FFAR1L3MBTL1MAPTKDM4ELDHA | |
| SCHEMBL5441988 | 0.75 | KDM4E (0.40) | FFAR1SLC6A4HRH3L3MBTL1MAPT | |
| SCHEMBL4910706 | 0.73 | GAA (0.46) | FFAR1SLC6A4MAPTKDM4EKMT2A | |
| SCHEMBL4907362 | 0.72 | MAPT (0.40) | SLC6A4HRH3CACNA1BMAPTCACNA1H | |
| SCHEMBL4899550 | 0.71 | CHRM2 (0.40) | SLC6A4HRH3CACNA1BMAPTCACNA1H | |
| SCHEMBL4906765 | 0.71 | KDM4E (0.65) | FFAR1L3MBTL1MAPTKDM4ELDHA | |
| SCHEMBL4906658 | 0.69 | MAPT (0.38) | SLC6A4HRH3MAPTKDM4EKMT2A | |
| SCHEMBL4910626 | 0.68 | HRH3 (0.51) | SLC6A4HRH3L3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746986-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-31 | — | — | EP | claimed |
| WO-2005097099-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | claimed |