SCHEMBL56019

SCHEMBL56019

Nc1nc2c(nc(Br)n2[C@@H]2O[C@H](CO)C(O)C2O)c(=O)[nH]1

nearest known ligand 0.79

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ PNP P00491 4/20 0.79
▸ MAPT P10636 2/20 0.65
▸ CYP3A4 P08684 1/20 0.65
▸ MEN1 O00255 2/20 0.58
▸ KMT2A Q03164 2/20 0.58
▸ ALDH1A1 P00352 1/20 0.56
▸ TLR7 Q9NYK1 2/20 0.55
▸ BLM P54132 1/20 0.55
▸ PMP22 Q01453 1/20 0.55
▸ TSHR P16473 1/20 0.55
▸ NFKB1 P19838 1/20 0.55
▸ NADK O95544 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ HSPA5 P11021 1/20 0.45
▸ HSPA8 P11142 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12150662 1.00 PNP (0.79) PNPMAPTCYP3A4MEN1KMT2A
SCHEMBL56018 1.00 PNP (0.79) PNPMAPTCYP3A4MEN1KMT2A
SCHEMBL14941501 1.00 PNP (0.79) PNPMAPTCYP3A4MEN1KMT2A
SCHEMBL12030980 1.00 PNP (0.79) PNPMAPTCYP3A4MEN1KMT2A
SCHEMBL10117789 1.00 PNP (0.79) PNPMAPTCYP3A4MEN1KMT2A
SCHEMBL23202308 1.00 PNP (0.79) PNPMAPTCYP3A4MEN1KMT2A
SCHEMBL12746818 1.00 PNP (0.79) PNPMAPTCYP3A4MEN1KMT2A
SCHEMBL2774442 1.00 PNP (0.79) PNPMAPTCYP3A4MEN1KMT2A
Water SCHEMBL5501671 0.99 PNP (0.78) PNPMAPTCYP3A4MEN1KMT2A
Water SCHEMBL5501677 0.99 PNP (0.78) PNPMAPTCYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4277 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4598504-A2 MICROPARTICLE AND IMPLANT FORMULATIONS FOR CGMP ANALOG THERAPY Mireca Medicines GmbH (DE) 2025-08-13 — — EP claimed
CN-120077132-A Modulation of SUV39H1 expression by RNA 姆内莫治疗公司 2025-05-30 — — CN claimed
US-20250115916-A1 MODULATION OF SUV39H1 EXPRESSION BY RNAS MNEMO THERAPEUTICS (FR) 2025-04-10 — — US claimed
EP-4466356-A1 MODULATION OF SUV39H1 EXPRESSION BY RNAS Mnemo Therapeutics (FR) 2024-11-27 — — EP claimed
WO-2024074585-A2 MICROPARTICLE AND IMPLANT FORMULATIONS FOR cGMP ANALOG THERAPY MIRECA MEDICINES GMBH (DE) 2024-04-11 — — WO claimed
EP-3353298-B1 ALLELE SELECTIVE GENE EDITING AND USES THEREOF ARCTURUS THERAPEUTICS INC (US) 2023-09-13 — — EP claimed
WO-2023139269-A1 MODULATION OF SUV39H1 EXPRESSION BY RNAS MNEMO THERAPEUTICS (FR) 2023-07-27 — — WO claimed
CN-112641951-B Bioactive supermolecule chiral hydrogel and preparation method and application thereof 河南工业大学 2023-03-28 — — CN claimed
CN-111804246-B Supermolecule eutectic solvent gel and preparation method and application thereof 河南工业大学 2022-06-14 — — CN claimed
CN-108350454-B Allele-selective gene editing and uses thereof 阿克丘勒斯治疗公司 2022-05-10 — — CN claimed
EP-1499187-A2 IMMUNOSTIMULATORY G,U-CONTAINING OLIGORIBONUCLEOTIDES Coley Pharmaceutical GmbH (DE) 2005-01-26 — — EP claimed
EP-0914110-B1 METHOD OF MODULATING MICROCIRCULATION NOVARTIS AG (CH) 2005-01-26 — — EP claimed
US-20040110717-A1 Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase MERCK SHARP & DOHME LLC 2004-06-10 — — US claimed
US-20040110718-A1 Anti-HCV nucleoside derivatives DEVOS RENE (GB) 2004-06-10 — — US claimed
US-20030232074-A1 For stimulating immune activation; for screening immunostimulatory compounds COLEY PHARMACEUTICAL GMBH (DE) 2003-12-18 — — US claimed
WO-2003086280-A2 IMMUNOSTIMULATORY G,U-CONTAINING OLIGORIBONUCLEOTIDES COLEY PHARMACEUTICAL GMBH (DE) 2003-10-23 — — WO claimed
US-20030008841-A1 Anti-HCV nucleoside derivatives F. HOFFMAN-LA ROCHE, A SWISS COMPANY (CH) 2003-01-09 — — US claimed
WO-2002057425-A2 NUCLEOSIDE DERIVATIVES AS INHIBITORS OF RNA-DEPENDENT RNA VIRAL POLYMERASE MERCK & CO., INC. (US) 2002-07-25 — — WO claimed
US-4746651-A ANTIBIOTIC AND ALDOGYCOSIDYL-GUANINE OR ISOXANTHOPTERIN IMMUNE RESPONSE-ENHANCING AGENT SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1988-05-24 — — US claimed
US-4539205-A Modulation of animal cellular responses with compositions containing 8-substituted guanine derivatives SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) 1985-09-03 — — US claimed
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