Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5600394 | 0.97 | KDM4E (0.36) | KDM4EATML3MBTL1GPR3POLB | |
| Fluoride Ion SCHEMBL5602127 | 0.97 | KDM4E (0.36) | KDM4EATML3MBTL1GPR3POLB | |
| Hydrochloric Acid SCHEMBL5603823 | 0.89 | KDM4E (0.31) | KDM4EATML3MBTL1 | |
| Bromide SCHEMBL5601721 | 0.86 | KDM4E (0.31) | KDM4EATM | |
| Hydrochloric Acid SCHEMBL5603956 | 0.84 | BIRC5 (0.32) | — | |
| Hydrochloric Acid SCHEMBL5599890 | 0.83 | MAPT (0.31) | — | |
| Fluoride Ion SCHEMBL5601530 | 0.83 | KDM4E (0.31) | KDM4EATM | |
| Hydrochloric Acid SCHEMBL5603930 | 0.83 | KDM4E (0.31) | KDM4EATM | |
| Bromide SCHEMBL5600682 | 0.81 | CA1 (0.39) | KDM4EL3MBTL1 | |
| Bromide SCHEMBL5600399 | 0.81 | CA1 (0.40) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |