Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10579226 | 0.99 | MAPT (0.44) | MAPTALDH1A1CHRM2DRD2DRD4 | |
| SCHEMBL16666944 | 0.92 | MAPT (0.55) | MAPTALDH1A1CHRM2DRD2DRD4 | |
| SCHEMBL19950805 | 0.91 | MAPT (0.48) | MAPTALDH1A1CHRM2KCNH3PPARG | |
| SCHEMBL25438578 | 0.89 | MAPT (0.46) | MAPTALDH1A1CHRM2DRD2DRD4 | |
| SCHEMBL6816046 | 0.89 | MAPT (0.46) | MAPTALDH1A1CHRM2DRD2DRD4 | |
| SCHEMBL41158 | 0.89 | MAPT (0.57) | MAPTALDH1A1CHRM2KCNH3PPARG | |
| SCHEMBL28828211 | 0.89 | MAPT (0.57) | MAPTALDH1A1CHRM2KCNH3PPARG | |
| Hydrochloric Acid SCHEMBL21813259 | 0.88 | MAPT (0.55) | MAPTALDH1A1CHRM2KCNH3PPARG | |
| SCHEMBL22393149 | 0.88 | MAPT (0.55) | MAPTALDH1A1CHRM2KCNH3PPARG | |
| Ammonia Solution, Strong SCHEMBL27657608 | 0.88 | MAPT (0.55) | MAPTALDH1A1CHRM2KCNH3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962716-B2 | Curable composition | KANEKA CORPORATION (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130116378-A1 | CURABLE COMPOSITION | KANEKA CORPORATION (JP) | 2013-05-09 | — | — | US | disclosed |
| US-20070299214-A1 | trimethoxysilyl-group-terminated polyoxypropylene polymer containing a reactive silicon group, and being crosslinkable through the formation of a siloxane bonding; neodecanoic acid or tin carbonate as curing catalyst; adhesion-imparting agent aminopropyltrimethoxysilane; one-component sealant, adhesives | KANEKA CORPORATION (JP) | 2007-12-27 | — | — | US | disclosed |