Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 16/20 | 0.58 |
| ▸ | PDE1A | P54750 | 7/20 | 0.56 |
| ▸ | PDE1B | Q01064 | 7/20 | 0.56 |
| ▸ | PDE1C | Q14123 | 7/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602775 | 0.95 | PDE5A (0.62) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL3607475 | 0.85 | PDE5A (0.70) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL8246208 | 0.81 | PDE5A (0.48) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL13316921 | 0.80 | PDE5A (0.48) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL8249160 | 0.79 | PDE5A (0.47) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL13316920 | 0.77 | PDE5A (0.52) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL8245321 | 0.76 | PDE5A (0.46) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL13316922 | 0.76 | PDE5A (0.52) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL13316917 | 0.75 | PDE5A (0.46) | PDE5APDE1APDE1BPDE1CKDM4E | |
| SCHEMBL8239311 | 0.75 | PDE5A (0.50) | PDE5APDE1APDE1BPDE1CKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | claimed |
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |