SCHEMBL5603538

SCHEMBL5603538

Cl[Zr](Cl)(C1C(n2cncn2)=Cc2ccccc21)C1C(n2cncn2)=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP2A6 P11509 1/20 0.33
ACHE P22303 1/20 0.33
LMNA P02545 1/20 0.32
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5602000 0.88 CYP2A6 (0.31) CYP2A6
SCHEMBL5599775 0.78 NOTUM (0.36) KDM4EALDH1A1SMN1; SMN2LMNA
SCHEMBL5602509 0.77 KDM4E (0.33) KDM4EALDH1A1SMN1; SMN2CYP2A6ACHE
SCHEMBL5602757 0.77 KDM4E (0.33) KDM4EALDH1A1SMN1; SMN2CYP2A6ACHE
SCHEMBL5602875 0.77 NOTUM (0.40) KDM4EALDH1A1
Hydrochloric Acid SCHEMBL5602751 0.77 CYP2A6 (0.38) KDM4EALDH1A1SMN1; SMN2CYP2A6ACHE
SCHEMBL5603615 0.76
Hydrochloric Acid SCHEMBL5602500 0.75 CYP2A6 (0.37) KDM4EALDH1A1SMN1; SMN2CYP2A6ACHE
SCHEMBL5601605 0.75
Hydrochloric Acid SCHEMBL5603530 0.75 CYP2A6 (0.37) KDM4EALDH1A1SMN1; SMN2CYP2A6ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed